Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.45 |
| ▸ | VNN1 | O95497 | 1/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 3/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PTGIR | P43119 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3823686 | 0.86 | BCL2A1 (0.47) | BCL2A1VNN1PDK1MAPK14PDK2 | |
| SCHEMBL3828503 | 0.85 | IKBKB (0.45) | BCL2A1VNN1PDK1MAPK14 | |
| SCHEMBL3826441 | 0.84 | MAPK14 (0.49) | BCL2A1VNN1PDK1MAPK14PDK2 | |
| SCHEMBL3822748 | 0.82 | BCL2A1 (0.52) | BCL2A1VNN1PDK1MAPK14PDK2 | |
| SCHEMBL3830084 | 0.79 | PDK1 (0.49) | BCL2A1VNN1PDK1MAPK14PDK2 | |
| SCHEMBL3829755 | 0.78 | PDK1 (0.48) | BCL2A1VNN1PDK1MAPK14PDK2 | |
| SCHEMBL3821700 | 0.77 | CNR2 (0.49) | BCL2A1VNN1PDK1MAPK14PDK2 | |
| SCHEMBL8179143 | 0.76 | BCL2A1 (0.46) | BCL2A1PDK1MAPK14PTGIRKMT2A | |
| SCHEMBL3822924 | 0.76 | BCL2A1 (0.46) | BCL2A1VNN1PDK1MAPK14PDK2 | |
| SCHEMBL3831162 | 0.76 | RAB9A (0.53) | BCL2A1PDK1MAPK14HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2097379-A1 | CARBOXAMIDE DERIVATIVES AS ION CHANNEL MODULATORS | Wyeth a Corporation of the State of Delaware (US) | 2009-09-09 | — | — | EP | claimed |
| WO-2008073936-A1 | CARBOXAMIDE DERIVATIVES AS ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |