Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3830104 | 1.00 | ALDH1A1 (0.58) | ALDH1A1MAPTHSD17B10S1PR3KDM4E | |
| SCHEMBL8870328 | 1.00 | ALDH1A1 (0.58) | ALDH1A1MAPTHSD17B10S1PR3KDM4E | |
| SCHEMBL1760833 | 0.83 | KDM4E (0.71) | ALDH1A1MAPTHSD17B10S1PR3KDM4E | |
| SCHEMBL1760831 | 0.83 | KDM4E (0.71) | ALDH1A1MAPTHSD17B10S1PR3KDM4E | |
| SCHEMBL2533522 | 0.83 | KDM4E (0.71) | ALDH1A1MAPTHSD17B10S1PR3KDM4E | |
| SCHEMBL21607172 | 0.83 | S1PR3 (0.49) | ALDH1A1S1PR3KDM4EALOX15 | |
| SCHEMBL21607177 | 0.83 | S1PR3 (0.49) | ALDH1A1S1PR3KDM4EALOX15 | |
| SCHEMBL1683590 | 0.83 | ALDH1A1 (0.50) | ALDH1A1MAPTHSD17B10S1PR3KDM4E | |
| SCHEMBL11184776 | 0.83 | ALDH1A1 (0.56) | ALDH1A1MAPTHSD17B10S1PR3KDM4E | |
| SCHEMBL16079679 | 0.82 | KDM4E (0.69) | ALDH1A1MAPTHSD17B10S1PR3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099778-A2 | AMIDO ANTI-VIRAL COMPOUNDS | Smithkline Beecham Corporation (US) | 2009-09-16 | — | — | EP | disclosed |
| US-20080181866-A1 | Amido Anti-viral Compounds | GENELABS TECHNOLOGIES, INC. | 2008-07-31 | — | — | US | disclosed |
| WO-2008064218-A2 | AMIDO ANTI-VIRAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-05-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080181866-A1 | Amido Anti-viral Compounds | ZC3HAV1, U2SURP, ZC3HAV1L | ALDH1A1 4630/4885MAPT 52/4885HSD17B10 4331/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.