Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 19/20 | 0.58 |
| ▸ | ITGA2B | P08514 | 18/20 | 0.58 |
| ▸ | ITGAV | P06756 | 9/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7463256 | 0.90 | ITGB3 (0.54) | ITGB3ITGA2BITGAV | |
| SCHEMBL7463260 | 0.86 | ITGB3 (0.49) | ITGB3ITGA2BITGAV | |
| SCHEMBL8459092 | 0.83 | ITGAV (0.56) | ITGB3ITGA2BITGAV | |
| SCHEMBL7664581 | 0.83 | ITGB3 (0.64) | ITGB3ITGA2BITGAV | |
| SCHEMBL8903718 | 0.81 | ITGB3 (0.53) | ITGB3ITGA2BITGAV | |
| SCHEMBL7490103 | 0.81 | ITGB3 (0.53) | ITGB3ITGA2BITGAV | |
| SCHEMBL383059 | 0.81 | ITGB3 (0.43) | ITGB3ITGA2BITGAV | |
| SCHEMBL8348648 | 0.81 | ITGB3 (0.52) | ITGB3ITGA2BITGAV | |
| SCHEMBL7658148 | 0.81 | ITGB3 (0.68) | ITGB3ITGA2BITGAV | |
| SCHEMBL28744974 | 0.79 | ITGB3 (0.48) | ITGB3ITGA2BITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | disclosed |
| US-6420558-B1 | COMPOUNDS WITH AMIDINE GROUPS ANTAGONISTIC ACTIVITY, CELL ADHESION INHIBITORY ACTIVITY, HUMAN PLATELET AGGREGATION INHIBITORY ACTIVITY, AND THERAPEUTIC AGENTS | MEIJI SEIKA KAISHA, LTD. (JP) | 2002-07-16 | — | — | US | disclosed |
| EP-1074543-A1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA KAISHA LTD. (JP) | 2001-02-07 | — | — | EP | disclosed |