Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | OGG1 | O15527 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 3/20 | 0.46 |
| ▸ | CNR2 | P34972 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HTR1B | P28222 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3816745 | 0.89 | ALDH1A1 (0.55) | ALDH1A1HPGDKDM4ETDP1TSHR | |
| SCHEMBL3816749 | 0.89 | ALDH1A1 (0.55) | ALDH1A1HPGDKDM4ETDP1TSHR | |
| SCHEMBL31404067 | 0.77 | KDM4E (0.62) | ALDH1A1HPGDKDM4ETDP1TSHR | |
| SCHEMBL12113399 | 0.76 | ALDH1A1 (0.53) | ALDH1A1HPGDKDM4ETDP1TSHR | |
| SCHEMBL12116456 | 0.75 | ALDH1A1 (0.55) | ALDH1A1HPGDKDM4ETDP1TSHR | |
| SCHEMBL12115952 | 0.74 | CNR2 (0.48) | ALDH1A1HPGDKDM4ETDP1TSHR | |
| SCHEMBL23785455 | 0.74 | TSHR (0.46) | ALDH1A1HPGDKDM4ETDP1TSHR | |
| SCHEMBL3830794 | 0.73 | KDM4E (0.46) | ALDH1A1HPGDKDM4ETDP1TSHR | |
| SCHEMBL1614613 | 0.73 | KDM4E (0.72) | ALDH1A1HPGDKDM4ETDP1TSHR | |
| SCHEMBL10724393 | 0.72 | CTSD (0.61) | ALDH1A1HPGDKDM4ETDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2089354-A1 | NAPHTHALENYLOXYPROPENYL DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Korea Research Institute Of Chemical Technology (KR) | 2009-08-19 | — | — | EP | disclosed |
| WO-2008054154-A1 | NAPHTHALENYLOXYPROPENYL DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-05-08 | — | — | WO | disclosed |