Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.63 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.63 |
| ▸ | PAM | P19021 | 2/20 | 0.54 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.52 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.52 |
| ▸ | PPARG | P37231 | 6/20 | 0.50 |
| ▸ | PPARD | Q03181 | 6/20 | 0.50 |
| ▸ | PPARA | Q07869 | 6/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.50 |
| ▸ | TLR2 | O60603 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | FABP4 | P15090 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9393812 | 1.00 | TSHR (0.63) | TSHRLMNANFKB1PMP22PAM | |
| SCHEMBL11262169 | 1.00 | TSHR (0.63) | TSHRLMNANFKB1PMP22PAM | |
| SCHEMBL6244496 | 0.97 | LMNA (0.61) | TSHRLMNANFKB1PMP22PAM | |
| Ammonia Solution, Strong SCHEMBL10346452 | 0.95 | LMNA (0.58) | TSHRLMNANFKB1PMP22PAM | |
| SCHEMBL8359442 | 0.93 | TSHR (0.55) | TSHRLMNANFKB1PMP22PAM | |
| SCHEMBL9558119 | 0.92 | SLC22A6 (0.61) | TSHRLMNANFKB1PMP22PAM | |
| Ethylene Glycol SCHEMBL10757160 | 0.90 | GPR84 (0.54) | TSHRLMNANFKB1PMP22PAM | |
| SCHEMBL3836400 | 0.89 | PAM (0.71) | TSHRLMNAPAMGPR84FFAR1 | |
| Octanedioate SCHEMBL6666833 | 0.89 | PAM (0.71) | TSHRLMNAPAMGPR84FFAR1 | |
| Sebacic Acid SCHEMBL6661482 | 0.89 | PAM (0.71) | TSHRLMNAPAMGPR84FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1448508-B1 | DOUBLE ESTERS | DRUG DISCOVERY LAB AS (NO) | 2009-09-23 | — | — | EP | claimed |
| EP-1448508-B1 | DOUBLE ESTERS | DRUG DISCOVERY LAB AS (NO) | 2009-09-23 | — | — | EP | disclosed |
| US-20050232865-A1 | Contrast agents | GE HEALTHCARE AS (NO) | 2005-10-20 | — | — | US | disclosed |
| US-20040131549-A1 | Ultrasonic diagnosis; crosslinked protein forming gas containing vesicles; stability; high speed elimination | NYCOMED IMAGING AS. | 2004-07-08 | — | — | US | disclosed |
| EP-0576521-B2 | IMPROVEMENTS IN OR RELATING TO CONTRAST AGENTS | AMERSHAM HEALTH AS (NO) | 2004-02-04 | — | — | EP | disclosed |
| US-20030031629-A1 | Contrast agents | NYCOMED IMAGING AS | 2003-02-13 | — | — | US | disclosed |
| US-5919753-A | Cross-linking agent | NYCOMED IMAGING AS (NO) | 1999-07-06 | — | — | US | disclosed |
| EP-0807441-A2 | Improvements in or relating to contrast agents | NYCOMED IMAGING AS (NO) | 1997-11-19 | — | — | EP | disclosed |
| EP-0576521-B1 | IMPROVEMENTS IN OR RELATING TO CONTRAST AGENTS | NYCOMED IMAGING AS (NO) | 1997-09-03 | — | — | EP | disclosed |
| US-5529766-A | Contrast agents | NYCOMED IMAGING AS (NO) | 1996-06-25 | — | — | US | disclosed |
| EP-0577659-B1 | CROSS-LINKING AGENT | NYCOMED IMAGING AS (NO) | 1996-01-17 | — | — | EP | disclosed |
| EP-0577659-A1 | CROSS-LINKING AGENT. | HOLMES MICHAEL JOHN (GB) | 1994-01-12 | — | — | EP | disclosed |
| EP-0576521-A1 | IMPROVEMENTS IN OR RELATING TO CONTRAST AGENTS. | NYCOMED IMAGING AS (NO) | 1994-01-05 | — | — | EP | disclosed |
| WO-1992017213-A1 | IMPROVEMENTS IN OR RELATING TO CONTRAST AGENTS | NYCOMED IMAGING AS (NO) | 1992-10-15 | — | — | WO | disclosed |
| WO-1992017436-A1 | CROSS-LINKING AGENT | HOLMES, MICHAEL, JOHN (GB) | 1992-10-15 | — | — | WO | disclosed |