Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | PAM | P19021 | 2/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 6/20 | 0.44 |
| ▸ | PPARD | Q03181 | 6/20 | 0.44 |
| ▸ | PPARA | Q07869 | 6/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.44 |
| ▸ | TLR2 | O60603 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | FABP4 | P15090 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8359130 | 0.93 | PAM (0.48) | TSHRLMNANFKB1PMP22PAM | |
| SCHEMBL3830872 | 0.93 | TSHR (0.63) | TSHRLMNANFKB1PMP22PAM | |
| SCHEMBL11262169 | 0.93 | TSHR (0.63) | TSHRLMNANFKB1PMP22PAM | |
| SCHEMBL9393812 | 0.93 | TSHR (0.63) | TSHRLMNANFKB1PMP22PAM | |
| SCHEMBL6244496 | 0.91 | LMNA (0.61) | TSHRLMNANFKB1PMP22PAM | |
| Ammonia Solution, Strong SCHEMBL10346452 | 0.88 | LMNA (0.58) | TSHRLMNANFKB1PMP22PAM | |
| SCHEMBL9558119 | 0.85 | SLC22A6 (0.61) | TSHRLMNANFKB1PMP22PAM | |
| SCHEMBL8814360 | 0.84 | PAM (0.42) | TSHRLMNANFKB1PMP22PAM | |
| Ethylene Glycol SCHEMBL10757160 | 0.84 | GPR84 (0.54) | TSHRLMNANFKB1PMP22PAM | |
| SCHEMBL3829618 | 0.83 | PAM (0.71) | TSHRLMNAPAMGPR84FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962626-A | BIODEGRADABLE POLYOXYETHYLENE GLYCOL MODIFIED WITH A FATTY ACID | NYCOMED IMAGING AS (NO) | 1999-10-05 | — | — | US | claimed |