SCHEMBL383183

SCHEMBL383183

COc1ccccc1C(=O)OO

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.59
ALDH1A1 P00352 1/20 0.59
CTSD P07339 1/20 0.58
NPC1 O15118 3/20 0.56
SMN1; SMN2 Q16637 3/20 0.56
MAPT P10636 2/20 0.56
ESR1 P03372 1/20 0.56
ESR2 Q92731 1/20 0.56
XBP1 P17861 1/20 0.56
NPSR1 Q6W5P4 1/20 0.56
STAT3 P40763 1/20 0.55
GAA P10253 2/20 0.54
TSHR P16473 1/20 0.54
MAPK1 P28482 1/20 0.54
HSD17B10 Q99714 1/20 0.54
KMT2A Q03164 1/20 0.54
HTT P42858 2/20 0.53
RAB9A P51151 3/20 0.53
ABCG2 Q9UNQ0 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methyl 2-Methoxybenzoate SCHEMBL29702077 0.87 TSHR (0.69) HPGDALDH1A1CTSDNPC1SMN1; SMN2
Methyl 2-Methoxybenzoate SCHEMBL196037 0.87 TSHR (0.69) HPGDALDH1A1CTSDNPC1SMN1; SMN2
SCHEMBL48968 0.87 HPGD (0.59) HPGDALDH1A1CTSDNPC1SMN1; SMN2
SCHEMBL446339 0.87 HPGD (0.59) HPGDALDH1A1CTSDNPC1SMN1; SMN2
Methyl 2-Methoxybenzoate SCHEMBL30744939 0.85 MAPT (0.67) HPGDALDH1A1CTSDNPC1SMN1; SMN2
SCHEMBL125031 0.83 HPGD (0.56) HPGDALDH1A1CTSDNPC1SMN1; SMN2
SCHEMBL8852648 0.83 HPGD (0.56) HPGDALDH1A1CTSDNPC1SMN1; SMN2
SCHEMBL16056712 0.83 HPGD (0.56) HPGDALDH1A1CTSDNPC1SMN1; SMN2
SCHEMBL17641437 0.83 CTSD (0.59) HPGDALDH1A1CTSDNPC1SMN1; SMN2
SCHEMBL31321657 0.83 ESR1 (0.66) HPGDALDH1A1CTSDNPC1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6951904-B1 Process for increasing the melt strength of polypropylene POLYMERS AUSTRALIA PTY LIMITED (AU) 2005-10-04 US claimed
EP-1080148-A4 PROCESS FOR INCREASING THE MELT STRENGTH OF POLYPROPYLENE POLYMERS AUSTRALIA PTY LTD (AU) 2003-02-05 EP claimed
EP-1080148-A1 PROCESS FOR INCREASING THE MELT STRENGTH OF POLYPROPYLENE Polymers Australia PTY Limited (AU) 2001-03-07 EP claimed
WO-1999036466-A1 PROCESS FOR INCREASING THE MELT STRENGTH OF POLYPROPYLENE POLYMERS AUSTRALIA PTY LIMITED (AU) 1999-07-22 WO claimed
EP-0149236-B1 PROCESS FOR THE PRODUCTION OF MOULDED BODIES WHICH ARE CELLULAR OR NOT BAYER AG (DE) 1988-07-20 EP claimed
EP-0149236-A2 Process for the production of moulded bodies which are cellular or not BAYER AG (DE) 1985-07-24 EP claimed
EP-3413726-B1 VITAMIN COMPOSITION NESTLE SA (CH) 2024-03-13 EP disclosed
EP-3983369-A1 PROCESS FOR THE PRODUCTION OF DIACYL PEROXIDES Nouryon Chemicals International B.V. (NL) 2022-04-20 EP disclosed
US-11203729-B2 Unsaturated macrocyclic epoxide as perfuming ingredient FIRMENICH SA (CH) 2021-12-21 US disclosed
WO-2021211923-A1 COMPOSITIONS AND METHODS FOR TREATING DISEASE PULMOQUINE THERAPEUTICS, INC. (US) 2021-10-21 WO disclosed
WO-2020249690-A1 PROCESS FOR THE PRODUCTION OF DIACYL PEROXIDES NOURYON CHEMICALS INTERNATIONAL B.V. (NL) 2020-12-17 WO disclosed
CN-106232786-B Unsaturated macrocyclic epoxides as perfuming ingredients 弗门尼舍有限公司 2020-08-07 CN disclosed
EP-3618613-A1 COMPOSITION CONTAINING CHLORINE DIOXIDE AND METHODS FOR USING SAME Pamel, Gregory J. (US) 2020-03-11 EP disclosed
EP-0149236-A2 Process for the production of moulded bodies which are cellular or not BAYER AG (DE) 1985-07-24 EP disclosed
US-4486327-A FOR PEROXYGEN COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 1984-12-04 US disclosed
US-4483778-A Peroxygen bleach activators and bleaching compositions THE PROCTER & GAMBLE COMPANY (US) 1984-11-20 US disclosed
EP-0102007-A2 Process for producing moulded articles which can be cellular BAYER AG (DE) 1984-03-07 EP disclosed
EP-0024680-B1 POWDER PAINT BINDERS AND PROCESS FOR THEIR PREPARATION BAYER AG (DE) 1982-06-09 EP disclosed
EP-0024680-A1 Powder paint binders and process for their preparation BAYER AG (DE) 1981-03-11 EP disclosed
US-3935138-A ADDITION COPOLYMER AND TRIGLYCIDYL ISOCYANURATE, BISOXAZOLINE OR TRIS-OXAZOLINE BAYER AKTIENGESELLSCHAFT (DT) 1976-01-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11203729-B2 Unsaturated macrocyclic epoxide as perfuming ingredient PTGES, TECR, EPHX2 HPGD 21/4885ALDH1A1 607/4885CTSD 2031/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.