SCHEMBL48968

SCHEMBL48968

COc1ccccc1C(=O)OOC(=O)c1ccccc1OC

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.59
ALDH1A1 P00352 1/20 0.59
CTSD P07339 1/20 0.58
MAPT P10636 2/20 0.56
ESR1 P03372 1/20 0.56
ESR2 Q92731 1/20 0.56
XBP1 P17861 1/20 0.56
NPSR1 Q6W5P4 1/20 0.56
STAT3 P40763 1/20 0.55
GAA P10253 1/20 0.54
TSHR P16473 1/20 0.54
MAPK1 P28482 1/20 0.54
HSD17B10 Q99714 1/20 0.54
KMT2A Q03164 1/20 0.54
HTT P42858 2/20 0.53
NPC1 O15118 3/20 0.53
RAB9A P51151 2/20 0.53
ABCG2 Q9UNQ0 1/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
L3MBTL1 Q9Y468 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7632556 0.92 HPGD (0.53) HPGDALDH1A1CTSDMAPTESR1
SCHEMBL6096882 0.92 MAPT (0.57) HPGDALDH1A1CTSDMAPTESR1
SCHEMBL7635707 0.91 HPGD (0.51) HPGDALDH1A1CTSDMAPTESR1
SCHEMBL14803675 0.91 LMNA (0.61) HPGDALDH1A1CTSDMAPTESR1
SCHEMBL7629471 0.88 HPGD (0.53) HPGDALDH1A1CTSDMAPTESR1
Methyl 2-Methoxybenzoate SCHEMBL29702077 0.87 TSHR (0.69) HPGDALDH1A1CTSDMAPTNPSR1
SCHEMBL446339 0.87 HPGD (0.59) HPGDALDH1A1CTSDMAPTESR1
Methyl 2-Methoxybenzoate SCHEMBL196037 0.87 TSHR (0.69) HPGDALDH1A1CTSDMAPTNPSR1
SCHEMBL383183 0.87 HPGD (0.59) HPGDALDH1A1CTSDMAPTESR1
SCHEMBL7625469 0.86 CTSD (0.50) HPGDALDH1A1CTSDMAPTESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 392 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11865374-B2 Functionalized polymers EVONIK OPERATIONS GMBH (DE) 2024-01-09 US claimed
US-20230312791-A1 FUNCTIONALIZED POLYMERS EVONIK OPERATIONS GMBH (DE) 2023-10-05 US claimed
EP-4200343-A1 FUNCTIONALIZED POLYMERS Evonik Operations GmbH (DE) 2023-06-28 EP claimed
CN-116096764-A Functionalized polymers 赢创运营有限公司 2023-05-09 CN claimed
WO-2022038054-A1 FUNCTIONALIZED POLYMERS EVONIK OPERATIONS GMBH (DE) 2022-02-24 WO claimed
EP-3957659-A1 FUNCTIONALIZED POLYMERS Evonik Operations GmbH (DE) 2022-02-23 EP claimed
EP-3710503-B1 FUNCTIONALIZED POLYMERS EVONIK OPERATIONS GMBH (DE) 2022-01-05 EP claimed
US-20200383896-A1 FUNCTIONALIZED POLYMERS EVONIK OPERATIONS GMBH (DE) 2020-12-10 US claimed
EP-3710503-A1 FUNCTIONALIZED POLYMERS Evonik Degussa GmbH (DE) 2020-09-23 EP claimed
CN-111356710-A Functionalized polymers 赢创运营有限公司 2020-06-30 CN claimed
US-20110086959-A1 SHEAR THINNING PEROXIDE DISPERSIONS ARKEMA INC. (US) 2011-04-14 US claimed
EP-2271677-A1 SHEAR THINNING PEROXIDE DISPERSIONS Arkema Inc. (US) 2011-01-12 EP claimed
WO-2010091035-A1 THIXOTROPIC ANHYDROUS SHEAR THINNING PEROXIDE DISPERSIONS ARKEMA INC. (US) 2010-08-12 WO claimed
WO-2009134950-A1 SHEAR THINNING PEROXIDE DISPERSIONS ARKEMA INC. (US) 2009-11-05 WO claimed
US-6951904-B1 Process for increasing the melt strength of polypropylene POLYMERS AUSTRALIA PTY LIMITED (AU) 2005-10-04 US claimed
EP-1080148-A4 PROCESS FOR INCREASING THE MELT STRENGTH OF POLYPROPYLENE POLYMERS AUSTRALIA PTY LTD (AU) 2003-02-05 EP claimed
EP-1080148-A1 PROCESS FOR INCREASING THE MELT STRENGTH OF POLYPROPYLENE Polymers Australia PTY Limited (AU) 2001-03-07 EP claimed
WO-1999036466-A1 PROCESS FOR INCREASING THE MELT STRENGTH OF POLYPROPYLENE POLYMERS AUSTRALIA PTY LIMITED (AU) 1999-07-22 WO claimed
EP-0149236-B1 PROCESS FOR THE PRODUCTION OF MOULDED BODIES WHICH ARE CELLULAR OR NOT BAYER AG (DE) 1988-07-20 EP claimed
EP-0056378-B1 AQEOUS SUSPENSIONS OF ORGANIC PEROXIDES INTEROX CHEMICALS PTY. LIMITED (AU) 1985-05-29 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11865374-B2 Functionalized polymers PUF60, PARN, PARG HPGD 1914/4885ALDH1A1 2598/4885CTSD 2888/4885
US-20200383896-A1 FUNCTIONALIZED POLYMERS PUF60, PARN, PARG HPGD 1914/4885ALDH1A1 2598/4885CTSD 2888/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.