Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 10/20 | 0.34 |
| ▸ | DRD3 | P35462 | 10/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | NPY2R | P49146 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | CCND1 | P24385 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL383373 | 0.85 | ITGB3 (0.40) | HDAC1NPY2RFFAR4 | |
| SCHEMBL382800 | 0.83 | ITGB3 (0.36) | DRD2DRD3HRH4HRH3NPY2R | |
| SCHEMBL382988 | 0.82 | PRMT5 (0.38) | DRD2DRD3 | |
| SCHEMBL381766 | 0.81 | DRD2 (0.42) | DRD2DRD3HDAC1MCHR1 | |
| SCHEMBL381747 | 0.81 | ITGB3 (0.37) | DRD2DRD3HDAC1 | |
| SCHEMBL381828 | 0.81 | DRD2 (0.43) | DRD2DRD3NPY2R | |
| SCHEMBL381826 | 0.80 | DRD2 (0.35) | DRD2DRD3EPHX2ADRA2AMCHR1 | |
| SCHEMBL382455 | 0.79 | DRD2 (0.42) | DRD2DRD3EPHX2 | |
| SCHEMBL6496356 | 0.79 | HDAC1 (0.41) | DRD2DRD3HDAC1 | |
| SCHEMBL383201 | 0.77 | ITGB3 (0.40) | DRD2DRD3EPHX2NPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | disclosed |