Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.45 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.45 |
| ▸ | POLA1 | P09884 | 2/20 | 0.40 |
| ▸ | TYMP | P19971 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.32 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ST6GAL1 | P15907 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL382322 | 0.87 | PDE4D (0.46) | PDE4DPDE3ASLC29A1POLA1TYMP | |
| SCHEMBL383426 | 0.85 | LMNA (0.42) | TYMPLMNATHRBMTORMDM2 | |
| SCHEMBL383885 | 0.81 | PDE4D (0.44) | PDE4DPDE3ASLC29A1POLA1TYMP | |
| SCHEMBL3789728 | 0.79 | LMNA (0.43) | TYMPLMNATHRBMTORMDM2 | |
| SCHEMBL383446 | 0.77 | PDE4D (0.46) | PDE4DPDE3ASLC29A1POLA1TYMP | |
| SCHEMBL383275 | 0.73 | LMNA (0.43) | TYMPLMNATHRBMTORMDM2 | |
| SCHEMBL3793139 | 0.71 | PDE4D (0.40) | PDE4DPDE3ASLC29A1POLA1TYMP | |
| SCHEMBL6680520 | 0.69 | PDE3A (0.55) | PDE4DPDE3ASLC29A1POLA1LMNA | |
| SCHEMBL26123700 | 0.69 | PDE4D (0.37) | PDE4DPDE3ASLC29A1POLA1TYMP | |
| SCHEMBL5710025 | 0.69 | TYMP (0.62) | TYMPLMNATHRBMTORMDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2408306-A1 | SUBSTITUTED NUCLEOSIDE AND NUCLEOTIDE ANALOGS | Alios Biopharma, Inc. (US) | 2012-01-25 | — | — | EP | disclosed |