SCHEMBL3834014

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10108512	0.91	HRH4 (0.83)	HRH4DRD4DRD2HRH2HRH1
	Isoloxapine SCHEMBL2738975	0.87	HRH4 (1.00)	HRH4DRD4DRD2HRH2HRH1
	SCHEMBL7256287	0.86	HRH4 (0.76)	HRH4DRD4DRD2HRH2HRH1
	SCHEMBL4192075	0.84	HRH4 (0.83)	HRH4DRD4DRD2HRH2HRH1
	SCHEMBL10152767	0.84	HRH4 (0.72)	HRH4DRD4DRD2HRH2HRH1
	SCHEMBL4188514	0.83	HRH4 (0.71)	HRH4DRD4DRD2HRH2HRH1
	Hydrochloric Acid SCHEMBL3838758	0.83	HRH4 (0.81)	HRH4DRD4DRD2HRH2HRH1
	SCHEMBL15963179	0.83	HRH4 (0.75)	HRH4DRD4DRD2HRH2HRH1
	Hydrochloric Acid SCHEMBL3836472	0.82	HRH4 (0.70)	HRH4DRD4DRD2HRH2HRH1
	SCHEMBL2738976	0.82	DRD4 (0.82)	HRH4DRD4DRD2HRH2HRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.