Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.34 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.33 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | TGM2 | P21980 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28436971 | 0.94 | TSHR (0.44) | TSHRLMNAHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL456287 | 0.94 | TSHR (0.44) | TSHRLMNAHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL29085234 | 0.92 | TSHR (0.42) | TSHRLMNAHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL28817694 | 0.92 | TSHR (0.42) | TSHRLMNAHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL28817681 | 0.92 | TSHR (0.42) | TSHRLMNAHPGDSMN1; SMN2ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL31228316 | 0.92 | TSHR (0.42) | TSHRLMNAHPGDSMN1; SMN2ALDH1A1 | |
| Acrylamide SCHEMBL27863437 | 0.83 | ZDHHC20 (0.44) | TSHRZDHHC20ZDHHC2TGM2 | |
| SCHEMBL5170699 | 0.81 | TSHR (0.56) | TSHRLMNAHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL20381429 | 0.81 | TAS1R3 (0.44) | TSHRALDH1A1ZDHHC20ZDHHC2TAS1R3 | |
| SCHEMBL2559046 | 0.81 | TAS1R3 (0.44) | TSHRALDH1A1ZDHHC20ZDHHC2TAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090041688-A1 | Sunless tanning compositions comprising certain substituted polyamine compounds and methods of use | DUEVA-KOGANOV OLGA | 2009-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090041688-A1 | Sunless tanning compositions comprising certain substituted polyamine compounds and methods of use | SRM, TYR, XPA | TSHR 1961/4885LMNA 1091/4885HPGD 585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.