SCHEMBL456287

SCHEMBL456287

C=CC(=O)NC(CC)CS(=O)(=O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.44
LMNA P02545 2/20 0.38
HPGD P15428 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
ZDHHC20 Q5W0Z9 1/20 0.37
ZDHHC2 Q9UIJ5 1/20 0.37
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
MMP1 P03956 1/20 0.36
MMP2 P08253 1/20 0.36
MMP8 P22894 1/20 0.36
CA9 Q16790 1/20 0.36
TAS1R3 Q7RTX0 3/20 0.35
TAS1R1 Q7RTX1 3/20 0.35
ALDH1A1 P00352 3/20 0.33
TGM2 P21980 2/20 0.33
POLB P06746 1/20 0.33
MAPK1 P28482 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28436971 1.00 TSHR (0.44) TSHRLMNAHPGDSMN1; SMN2ZDHHC20
Ammonia Solution, Strong SCHEMBL31228316 0.98 TSHR (0.42) TSHRLMNAHPGDSMN1; SMN2ZDHHC20
SCHEMBL28817694 0.98 TSHR (0.42) TSHRLMNAHPGDSMN1; SMN2ZDHHC20
SCHEMBL29085234 0.98 TSHR (0.42) TSHRLMNAHPGDSMN1; SMN2ZDHHC20
SCHEMBL28817681 0.98 TSHR (0.42) TSHRLMNAHPGDSMN1; SMN2ZDHHC20
Acrylamide SCHEMBL3834772 0.94 TSHR (0.39) TSHRLMNAHPGDSMN1; SMN2ZDHHC20
SCHEMBL5170699 0.87 TSHR (0.56) TSHRLMNAHPGDSMN1; SMN2ZDHHC20
SCHEMBL20381429 0.86 TAS1R3 (0.44) TSHRZDHHC20ZDHHC2TAS1R3TAS1R1
SCHEMBL2559046 0.86 TAS1R3 (0.44) TSHRZDHHC20ZDHHC2TAS1R3TAS1R1
SCHEMBL22399756 0.85 TSHR (0.42) TSHRLMNAHPGDSMN1; SMN2ZDHHC20

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1231 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12618000-B2 Friction reduction of acidic treatment fluids HALLIBURTON ENERGY SERVICES, INC. (US) 2026-05-05 US claimed
US-20250066661-A1 INVERTING PACKAGES, EMULSIONS, AND METHODS STERLING SPECIALTY CHEMICALS HOLDING UK LIMITED (GB) 2025-02-27 US claimed
US-20250051635-A1 FRICTION REDUCTION OF ACIDIC TREATMENT FLUIDS HALLIBURTON ENERGY SERVICES, INC. (US) 2025-02-13 US claimed
EP-3347446-B1 A STABLE LAUNDRY OR CLEANING COMPOSITION, PROCESS FOR PREPARING THE SAME, AND METHOD OF USE ISP INVESTMENTS LLC (US) 2024-12-11 EP claimed
US-12139667-B1 Friction reduction of acidic treatment fluids HALLIBURTON ENERGY SERVICES, INC. (US) 2024-11-12 US claimed
US-11753580-B2 Inverse emulsion compositions KEMIRA OYJ (FI) 2023-09-12 US claimed
US-11638950-B2 Articles prepared using curable compositions based on polymerizable ionic species ARKEMA FRANCE (FR) 2023-05-02 US claimed
EP-3387025-B1 INVERSE EMULSION COMPOSITIONS KEMIRA OYJ (FI) 2023-04-26 EP claimed
US-11597002-B2 2023-03-07 US claimed
US-11591505-B2 High density fluid for completion applications TERVES, LLC (US) 2023-02-28 US claimed
US-20050086745-A1 Oxidation dyeing composition for keratinous fibres on amphiphilic polymers of at least an ethylenically unsaturated monomer with sulphonic group and comprising a hydrophobic part L'OREAL (FR) 2005-04-28 US claimed
CN-1492753-A Oxidizing composition for treating keratin materials, based on at least one ethylenically unsaturated monomer containing sulphonic groups and an amphiphilic polymer comprising hydrophobic portions �ź㴫 2004-04-28 CN claimed
US-20040074015-A1 Oxidising composition for treating keratinous materials based on amphiphilic polymers of at least an ethylenically unsaturated monomer containing a sulfonic group and comprising a hydrophobic part L'OREAL (FR) 2004-04-22 US claimed
US-20040071641-A1 Photoprotective/cosmetic compositions comprising sulfonic/hydrophobic amphiphilic polymers SOCIETE L'OREAL S.A. (FR) 2004-04-15 US claimed
US-20040062728-A1 Photoprotective compositions comprising sulfonic/hydrophobic amphiphilic polymers SOCIETE L'OREAL, S.A. (FR) 2004-04-01 US claimed
US-20030157047-A1 Cosmetic composition for removing make-up from and clening the skin L'OREAL (FR) 2003-08-21 US claimed
US-20030108577-A1 Cosmetic and/or dermatological acid composition containing an amphiphilic polymer L'OREAL (FR) 2003-06-12 US claimed
US-20030050201-A1 Cleansing composition containing an amphiphilic polymer L'OREAL (FR) 2003-03-13 US claimed
US-20030036490-A1 Stable composition with high electrolyte content containing an amphiphilic polymer L'OREAL (FR) 2003-02-20 US claimed
US-4296016-A Method of preparing a polymeric electrolyte particularly for an electro-optical device EBAUCHES S.A. (CH) 1981-10-20 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030157047-A1 Cosmetic composition for removing make-up from and clening the skin CUTA, DEGS1, LAGE3 TSHR 3898/4885LMNA 239/4885HPGD 2144/4885
US-20050086745-A1 Oxidation dyeing composition for keratinous fibres on amphiphilic polymers of at least an ethylenically unsaturated monomer with sulphonic group and comprising a hydrophobic part KRT18, ELOVL5, DSG1 TSHR 4743/4885LMNA 718/4885HPGD 353/4885
US-20040062728-A1 Photoprotective compositions comprising sulfonic/hydrophobic amphiphilic polymers CUTA, PCNA, DSG1 TSHR 4532/4885LMNA 224/4885HPGD 253/4885
US-20040071641-A1 Photoprotective/cosmetic compositions comprising sulfonic/hydrophobic amphiphilic polymers CUTA, DSG1, PCNA TSHR 3779/4885LMNA 153/4885HPGD 628/4885
US-20030108577-A1 Cosmetic and/or dermatological acid composition containing an amphiphilic polymer KRT18, DSG1, CUTA TSHR 3699/4885LMNA 529/4885HPGD 515/4885
US-20030036490-A1 Stable composition with high electrolyte content containing an amphiphilic polymer KRT18, DSG1, SCNN1A TSHR 3246/4885LMNA 522/4885HPGD 2025/4885
US-20040074015-A1 Oxidising composition for treating keratinous materials based on amphiphilic polymers of at least an ethylenically unsaturated monomer containing a sulfonic group and comprising a hydrophobic part KRT18, DSG1, CUTA TSHR 4775/4885LMNA 536/4885HPGD 572/4885
US-12618000-B2 Friction reduction of acidic treatment fluids GFER, FGB, NSF TSHR 1564/4885LMNA 3508/4885HPGD 3490/4885
US-20030050201-A1 Cleansing composition containing an amphiphilic polymer UGCG, SGMS1, SGMS2 TSHR 3829/4885LMNA 1266/4885HPGD 1907/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.