SCHEMBL3835294

SCHEMBL3835294

O=[C]Oc1ccccc1C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 10/20 0.55
ALDH1A1 P00352 9/20 0.55
HSD17B10 Q99714 6/20 0.55
HPGD P15428 6/20 0.55
HMGB1 P09429 2/20 0.55
NAPRT Q6XQN6 2/20 0.55
ESR1 P03372 1/20 0.55
ITGB3 P05106 1/20 0.55
ITGA2B P08514 1/20 0.55
TSHR P16473 1/20 0.55
GGT1 P19440 1/20 0.55
PTGS1 P23219 1/20 0.55
PTGS2 P35354 1/20 0.55
BLM P54132 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
MAPT P10636 2/20 0.53
USP2 O75604 1/20 0.53
PDE3A Q14432 1/20 0.53
ALOX15 P16050 1/20 0.52
HTT P42858 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5633418 0.82 ELANE (0.54) KDM4EALDH1A1HSD17B10HPGDHMGB1
SCHEMBL7486996 0.82 LMNA (0.53) KDM4EALDH1A1HSD17B10HPGDHMGB1
SCHEMBL10861605 0.82 KDM4E (0.53) KDM4EALDH1A1HSD17B10HPGDHMGB1
SCHEMBL7120215 0.81 CES2 (0.50) KDM4EALDH1A1HSD17B10HPGDHMGB1
SCHEMBL5710942 0.80 MAPT (0.56) KDM4EALDH1A1HSD17B10HPGDTSHR
SCHEMBL2450196 0.79 KDM4E (0.55) KDM4EALDH1A1HSD17B10HPGDHMGB1
SCHEMBL6150783 0.78 TP53 (0.45) ALDH1A1HPGDMAPTUSP2KMT2A
SCHEMBL446113 0.78 HTT (0.77) KDM4EALDH1A1HSD17B10HPGDHMGB1
SCHEMBL29682980 0.78 HTT (0.77) KDM4EALDH1A1HSD17B10HPGDHMGB1
SCHEMBL29010714 0.78 KDM4E (0.63) KDM4EALDH1A1HSD17B10HPGDHMGB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5238909-A For preemergence or postemergence use EASTMAN KODAK COMPANY (US) 1993-08-24 US claimed
EP-0476760-A2 4-substituted isoxazole herbicides EASTMAN KODAK COMPANY (US) 1992-03-25 EP claimed
US-10358567-B2 Compound, ink, ink cartridge and ink jet recording method CANON KABUSHIKI KAISHA (JP) 2019-07-23 US disclosed
US-20170247557-A1 COMPOUND, INK, INK CARTRIDGE AND INK JET RECORDING METHOD CANON KABUSHIKI KAISHA (JP) 2017-08-31 US disclosed
EP-1522559-B1 WATER-SOLUBLE COMPLEX DYE, RECORDING FLUID, AND METHOD OF RECORDING MITSUBISHI CHEM CORP (JP) 2009-09-16 EP disclosed
US-7097700-B2 Water-soluble complex dye, recording fluid and recording method MITSUBISHI CHEMICAL CORPORATION (JP) 2006-08-29 US disclosed
US-7094280-B2 Water-soluble complex dye, recording fluid and recording method MITSUBISHI CHEMICAL CORPORATION (JP) 2006-08-22 US disclosed
US-7025815-B2 Water-soluble complex dye, recording fluid and recording method MITSUBISHI CHEMICAL CORPORATION (JP) 2006-04-11 US disclosed
US-20050109237-A1 Water-soluble complex dye, recording fluid and recording method MITSUBISHI CHEMICAL CORPORATION (JP) 2005-05-26 US disclosed
EP-1533345-A1 WATER-SOLUBLE COMPLEX DYE, RECORDING FLUID, AND METHOD OF RECORDING Mitsubishi Chemical Corporation (JP) 2005-05-25 EP disclosed
US-20050103225-A1 Water-soluble complex dye, recording fluid and recording method MITSUBISHI CHEMICAL CORPORATION (JP) 2005-05-19 US disclosed
US-20050081747-A1 Water-soluble complex dye, recording fluid and recording method MITSUBISHI CHEMICAL CORPORATION (JP) 2005-04-21 US disclosed
EP-1522559-A1 WATER-SOLUBLE COMPLEX DYE, RECORDING FLUID, AND METHOD OF RECORDING Mitsubishi Chemical Corporation (JP) 2005-04-13 EP disclosed
EP-1522558-A1 WATER-SOLUBLE COMPLEX DYE, RECORDING FLUID, AND METHOD OF RECORDING Mitsubishi Chemical Corporation (JP) 2005-04-13 EP disclosed
US-5238909-A For preemergence or postemergence use EASTMAN KODAK COMPANY (US) 1993-08-24 US disclosed
EP-0476760-A2 4-substituted isoxazole herbicides EASTMAN KODAK COMPANY (US) 1992-03-25 EP disclosed
US-4933355-A ALDOSE REDUCTASE INHIBITORS SANKYO COMPANY LIMITED (JP) 1990-06-12 US disclosed
EP-0337819-A1 Thiazole derivatives, their preparation and their use in the treatment of diabetes complications Sankyo Company Limited (JP) 1989-10-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10358567-B2 Compound, ink, ink cartridge and ink jet recording method JAK1, JAK2, ETV6 KDM4E 440/4885ALDH1A1 176/4885HSD17B10 3367/4885
US-20170247557-A1 COMPOUND, INK, INK CARTRIDGE AND INK JET RECORDING METHOD JAK1, JAK2, ETV6 KDM4E 440/4885ALDH1A1 176/4885HSD17B10 3367/4885
US-20050103225-A1 Water-soluble complex dye, recording fluid and recording method IK, ROR1, WNT1 KDM4E 3092/4885ALDH1A1 1391/4885HSD17B10 3512/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.