Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 3/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL224619 | 0.81 | MRGPRX4 (0.45) | MRGPRX4ADRA1DADRA1AADRA1B | |
| SCHEMBL2741621 | 0.79 | ADRA1D (0.42) | ADRA1DADRA1AADRA1B | |
| SCHEMBL224383 | 0.78 | HRH3 (0.40) | FFAR1PPARGMAOAMAOB | |
| SCHEMBL3835629 | 0.78 | MRGPRX4 (0.36) | FFAR1PPARDMRGPRX4PPARGMAOA | |
| SCHEMBL2741622 | 0.69 | ADRA1D (0.44) | ADRA1DADRA1AADRA1B | |
| SCHEMBL2741620 | 0.69 | TAAR1 (0.47) | ADRA1DADRA1AADRA1B | |
| SCHEMBL222298 | 0.67 | FFAR1 (0.43) | FFAR1PPARGMAOAMAOB | |
| SCHEMBL222797 | 0.67 | MRGPRX4 (0.43) | MRGPRX4MAOAMAOB | |
| SCHEMBL22396973 | 0.61 | ATF4 (0.63) | — | |
| SCHEMBL2741624 | 0.60 | SOD1 (0.41) | ADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2094668-A2 | 4-IMIDAZOLINES AS TAAR'S LIGANDS | F. Hoffmann-Roche AG (CH) | 2009-09-02 | — | — | EP | claimed |
| WO-2008074679-A2 | 4-IMIDAZOLINES AS TAAR'S LIGANDS | F. HOFFMANN-LA ROCHE AG (CH) | 2008-06-26 | — | — | WO | claimed |