Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3835625 | 0.78 | FFAR1 (0.35) | MRGPRX4FFAR1PPARDMAOAMAOB | |
| SCHEMBL224619 | 0.67 | MRGPRX4 (0.45) | MRGPRX4 | |
| SCHEMBL2741621 | 0.64 | ADRA1D (0.42) | — | |
| SCHEMBL224383 | 0.62 | HRH3 (0.40) | FFAR1MAOAMAOBPPARG | |
| SCHEMBL22396973 | 0.62 | ATF4 (0.63) | — | |
| SCHEMBL29828846 | 0.58 | MRGPRX4 (0.69) | MRGPRX4FFAR1PPARDMAOAMAOB | |
| SCHEMBL7214701 | 0.58 | MRGPRX4 (0.69) | MRGPRX4FFAR1PPARDMAOAMAOB | |
| SCHEMBL30046670 | 0.58 | HRH3 (0.40) | MAOAMAOBPPARG | |
| SCHEMBL14359475 | 0.58 | KCNA3 (0.48) | MRGPRX4MAOAMAOB | |
| SCHEMBL3839877 | 0.57 | FFAR1 (0.34) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2094668-A2 | 4-IMIDAZOLINES AS TAAR'S LIGANDS | F. Hoffmann-Roche AG (CH) | 2009-09-02 | — | — | EP | claimed |
| WO-2008074679-A2 | 4-IMIDAZOLINES AS TAAR'S LIGANDS | F. HOFFMANN-LA ROCHE AG (CH) | 2008-06-26 | — | — | WO | claimed |