SCHEMBL38363

SCHEMBL38363

O=P(O)(O)OP(=O)(O)OP(=O)(O)S

nearest known ligand 0.53

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FDPS P14324 1/20 0.53
BLM P54132 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
BTN3A1 O00481 4/20 0.38
MVD P53602 3/20 0.33
ENPP1 P22413 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29225919 0.97 FDPS (0.50) FDPSBLMTDP1BTN3A1MVD
SCHEMBL3823202 0.97 FDPS (0.50) FDPSBLMTDP1BTN3A1MVD
SCHEMBL1274886 0.87
SCHEMBL333910 0.87
Triphosphate SCHEMBL18714 0.87 FDPS (0.69) FDPSBLMTDP1BTN3A1MVD
Triphosphate SCHEMBL15555988 0.87 FDPS (0.69) FDPSBLMTDP1BTN3A1MVD
Triphosphate SCHEMBL29692 0.85 FDPS (0.50) FDPSBLMTDP1BTN3A1MVD
Ammonia Solution, Strong SCHEMBL5049158 0.84 FDPS (0.56) FDPSBLMTDP1BTN3A1
Triphosphate SCHEMBL25284822 0.83 FDPS (0.64) FDPSBLMTDP1BTN3A1MVD
SCHEMBL897837 0.83 FDPS (0.64) FDPSBLMTDP1BTN3A1MVD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1796 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4590683-A1 NOVEL PHOSPHOROUS (V)-BASED REAGENTS, PROCESSES FOR THE PREPARATION THEREOF, AND THEIR USE IN MAKING STEREO-DEFINED ORGANOPHOSHOROUS (V) COMPOUNDS Bristol-Myers Squibb Company (US) 2025-07-30 EP claimed
EP-4561631-A2 MODIFIED OLIGONUCLEOTIDES AND DOUBLE-STRANDED RNAS Alnylam Pharmaceuticals, Inc. (US) 2025-06-04 EP claimed
CN-118516431-A Novel method for producing oligonucleotides 葛兰素史克知识产权开发有限公司 2024-08-20 CN claimed
US-20240209406-A1 ENZYMATIC SYNTHESIS OF NTP AND NQP CODEXIS, INC. 2024-06-27 US claimed
WO-2024129235-A1 ENZYMATIC SYNTHESIS OF NTP AND NQP CODEXIS, INC. (US) 2024-06-20 WO claimed
CN-111479923-B Novel method for producing oligonucleotides 葛兰素史克知识产权开发有限公司 2024-06-18 CN claimed
US-20240166675-A1 NOVEL PHOSPHOROUS (V)-BASED REAGENTS, PROCESSES FOR THE PREPARATION THEREOF, AND THEIR USE IN MAKING STEREO-DEFINED ORGANOPHOSHOROUS (V) COMPOUNDS BRISTOL-MYERS SQUIBB COMPANY 2024-05-23 US claimed
EP-4370132-A2 MULTIPLEXING TARGETING LIGANDS THROUGH CLICK CHEMISTRY AT THE ANOMERIC SITE OF SUGARS Alnylam Pharmaceuticals, Inc. (US) 2024-05-22 EP claimed
EP-4370136-A2 SIMPLE CHEMICAL APPROACHES TO INTRODUCE 2,6-DIAMINOPURINE AND 2-AMINOADENINE CONJUGATES INTO OLIGONUCLEOTIDES Alnylam Pharmaceuticals, Inc. (US) 2024-05-22 EP claimed
EP-4367125-A1 AMINOOXY CLICK CHEMISTRY (AOCC): A VERSATILE BIOCONJUGATION APPROACH Alnylam Pharmaceuticals, Inc. (US) 2024-05-15 EP claimed
EP-0914462-A1 TARGET NUCLEIC ACID SEQUENCE AMPLIFICATION MOLECULAR BIOLOGY RESOURCES, INC. (US) 1999-05-12 EP claimed
EP-0866796-A1 IMPROVEMENTS IN OR RELATING TO MUTAGENESIS OF NUCLEIC ACIDS MEDICAL RESEARCH COUNCIL (GB) 1998-09-30 EP claimed
WO-1998013523-A1 METHOD OF SEQUENCING DNA PYROSEQUENCING AB (SE) 1998-04-02 WO claimed
WO-1997035026-A1 TARGET NUCLEIC ACID SEQUENCE AMPLIFICATION MOLECULAR BIOLOGY RESOURCES, INC. (US) 1997-09-25 WO claimed
WO-1997011083-A1 IMPROVEMENTS IN OR RELATING TO MUTAGENESIS OF NUCLEIC ACIDS MEDICAL RESEARCH COUNCIL (GB) 1997-03-27 WO claimed
US-5525471-A INCORPORATION OF NUCLEOSIDE ANALOGS TO PREVENT SUBSEQUENT EXONUCLEASE ATTACK THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1996-06-11 US claimed
US-4728730-A Synthesis of nucleoside thiophosphoanhydrides WISCONSIN ALUMINI RESEARCH FOUNDATION (US) 1988-03-01 US claimed
EP-0183800-A1 METHOD OF DETECTION NUCLEIC ACID SEQUENCES RODLAND, Karin D. (US) 1986-06-11 EP claimed
WO-1985005642-A1 METHOD OF DETECTION NUCLEIC ACID SEQUENCES RODLAND KARIN D 1985-12-19 WO claimed
US-4521509-A Method for degrading DNA RESEARCH CORPORATION (US) 1985-06-04 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240166675-A1 NOVEL PHOSPHOROUS (V)-BASED REAGENTS, PROCESSES FOR THE PREPARATION THEREOF, AND THEIR USE IN MAKING STEREO-DEFINED ORGANOPHOSHOROUS (V) COMPOUNDS PPIP5K2, NUDT1, NT5C3B FDPS 18/4885BLM 1756/4885TDP1 1095/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.