Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrahydrofuran SCHEMBL28083180 | 0.84 | ALDH1A1 (0.53) | ALDH1A1 | |
| Tetrahydrofuran SCHEMBL377183 | 0.84 | ALDH1A1 (0.53) | ALDH1A1KEAP1SMN1; SMN2 | |
| SCHEMBL107627 | 0.79 | NFKB1 (0.43) | ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL9315030 | 0.76 | NFKB1 (0.40) | ALDH1A1 | |
| Tetrahydrofuran SCHEMBL29000689 | 0.76 | ALDH1A1 (0.57) | ALDH1A1 | |
| Tetrahydrofuran SCHEMBL1728990 | 0.75 | DNM1 (0.46) | ALDH1A1KEAP1SMN1; SMN2 | |
| Tetrahydrofuran SCHEMBL9015780 | 0.75 | DNM1 (0.46) | ALDH1A1KEAP1SMN1; SMN2 | |
| Tetrahydrofuran SCHEMBL28585403 | 0.75 | DNM1 (0.46) | ALDH1A1KEAP1SMN1; SMN2 | |
| Tetrahydrofuran SCHEMBL288894 | 0.74 | TDP1 (0.40) | ALDH1A1KEAP1SMN1; SMN2 | |
| Tetrahydrofuran SCHEMBL8250456 | 0.73 | DNM1 (0.43) | ALDH1A1KEAP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4010348-A1 | (2-ACETAMIDYL)THIO-BETA-D-GALACTOPYRANOSIDE DERIVATIVES | Idorsia Pharmaceuticals Ltd (CH) | 2022-06-15 | — | — | EP | disclosed |
| WO-2021028323-A1 | (2-ACETAMIDYL)THIO-BETA-D-GALACTOPYRANOSIDE DERIVATIVES | IDORSIA PHARMACEUTICALS LTD (CH) | 2021-02-18 | — | — | WO | disclosed |
| EP-2134346-A1 | INHIBITORS OF JANUS KINASES AND/OR 3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE-1 | Merck & Co., Inc. (US) | 2009-12-23 | — | — | EP | disclosed |
| WO-2008112217-A1 | INHIBITORS OF JANUS KINASES AND/OR 3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE-1 | MERCK & CO., INC. (US) | 2008-09-18 | — | — | WO | disclosed |