Styrene

Styrene

SCHEMBL3837504

C=C(C)C(=O)OC.C=Cc1ccccc1.CC(C#N)=CC=Cc1ccccc1.O=C1C=CC(=O)N1c1ccccc1

nearest known ligand 0.38

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Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 6/20 0.38
KMT2A Q03164 2/20 0.38
MCL1 Q07820 2/20 0.37
ALDH1A1 P00352 5/20 0.36
KDM4E B2RXH2 2/20 0.36
HPGD P15428 2/20 0.36
MAPT P10636 2/20 0.36
HTT P42858 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
MGLL Q99685 1/20 0.35
APP P05067 1/20 0.34
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2C9 P11712 1/20 0.32
MEN1 O00255 1/20 0.32
CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL27938281 0.90 MGLL (0.43) LMNAKMT2AMCL1ALDH1A1KDM4E
Styrene SCHEMBL8564811 0.90 LMNA (0.45) LMNAKMT2AMCL1ALDH1A1KDM4E
Styrene SCHEMBL20970201 0.87 MGLL (0.46) KMT2AALDH1A1HPGDMAPTHTT
Styrene SCHEMBL3838357 0.86 MGLL (0.41) KMT2AALDH1A1HPGDMAPTHTT
SCHEMBL1032682 0.85 LMNA (0.49) LMNAKMT2AMCL1ALDH1A1KDM4E
Benzene SCHEMBL28172055 0.84 MGLL (0.49) LMNAKMT2AMCL1ALDH1A1KDM4E
Styrene SCHEMBL28228550 0.81 MGLL (0.41) LMNAKMT2AALDH1A1HPGDMAPT
Styrene SCHEMBL27514094 0.81 MGLL (0.37) LMNAKMT2AALDH1A1HPGDMAPT
Styrene SCHEMBL28850634 0.81 MGLL (0.40) LMNAKMT2AALDH1A1HPGDMAPT
Styrene SCHEMBL7923087 0.80 MGLL (0.36) KMT2AALDH1A1MAPTMGLLMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1123350-B1 POLYCARBONATE RESIN BLENDS CONTAINING TITANIUM DIOXIDE SABIC INNOVATIVE PLASTICS IP (NL) 2009-10-07 EP disclosed
EP-1123350-A1 POLYCARBONATE RESIN BLENDS CONTAINING TITANIUM DIOXIDE GENERAL ELECTRIC COMPANY (US) 2001-08-16 EP disclosed
US-6133360-A INJECTION MOLDING USING A TITANIUM DIOXIDE CONTAINING POLYCARBONATE RESIN WHREIN TITANIUM DIOXIDE IS COATED WITH A SINGLE COAT AND FORMING MOLDINGS HAVING NO STREAKING GENERAL ELECTRIC COMPANY (US) 2000-10-17 US disclosed
WO-2000024828-A1 POLYCARBONATE RESIN BLENDS CONTAINING TITANIUM DIOXIDE GENERAL ELECTRIC COMPANY (US) 2000-05-04 WO disclosed
EP-0363814-A2 Low-temperature impact blends of polycarbonate, graft copolymer and rigid copolymer GENERAL ELECTRIC COMPANY (US) 1990-04-18 EP disclosed
US-4855357-A WITH UNSATURATED MONOMERS GRAFTED TO RUBBER POLYMER SUBSTRATES AND RIGID COMPATIBLE ADDITION COPOLYMERS GENERAL ELECTRIC COMPANY (US) 1989-08-08 US disclosed