SCHEMBL3837591

SCHEMBL3837591

OB(O)c1cc(C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)cc(C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)c1

nearest known ligand 0.41

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 2/20 0.41
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10825969 0.82 LMNA (0.43) LMNA
SCHEMBL3142156 0.80 MGLL (0.57) MGLL
SCHEMBL5076176 0.76
SCHEMBL7611310 0.76
SCHEMBL11046804 0.75 NR1H2 (0.36) LMNA
SCHEMBL10574915 0.75 NR1H2 (0.36) LMNA
SCHEMBL11046808 0.75 LMNA (0.33) LMNA
SCHEMBL126169 0.73 MGLL (0.61) MGLLLMNA
SCHEMBL4933973 0.72 LMNA (0.40) LMNA
SCHEMBL5137828 0.72 LMNA (0.35) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3221297-B1 PROCESS FOR THE SYNTHESIS OF BENZAZEPINE DERIVATIVES RICHTER GEDEON NYRT (HU) 2018-08-22 EP disclosed
EP-3221297-A1 PROCESS FOR THE SYNTHESIS OF BENZAZEPINE DERIVATIVES Richter Gedeon Nyrt. (HU) 2017-09-27 EP disclosed
WO-2016079684-A1 PROCESS FOR THE SYNTHESIS OF BENZAZEPINE DERIVATIVES RICHTER GEDEON NYRT. (HU) 2016-05-26 WO disclosed
EP-2107067-A1 Boron catalysed peptide synthesis DSM IP Assets B.V. (NL) 2009-10-07 EP disclosed