SCHEMBL3142156

SCHEMBL3142156

OB(O)c1ccc(C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)cc1

nearest known ligand 0.57

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 3/20 0.57
TRPV6 Q9H1D0 2/20 0.42
ORAI1 Q96D31 1/20 0.42
ORAI2 Q96SN7 1/20 0.42
ORAI3 Q9BRQ5 1/20 0.42
ENPP2 Q13822 4/20 0.38
CA2 P00918 3/20 0.37
CA1 P00915 2/20 0.37
LPL P06858 2/20 0.37
LIPG Q9Y5X9 2/20 0.37
TSHR P16473 1/20 0.37
TRPV1 Q8NER1 3/20 0.35
CA4 P22748 1/20 0.34
CA6 P23280 1/20 0.34
CA5A P35218 1/20 0.34
CA7 P43166 1/20 0.34
CA14 Q9ULX7 1/20 0.34
CA5B Q9Y2D0 1/20 0.34
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL164370 0.83 MGLL (0.67) MGLLTRPV6ORAI1ORAI2ORAI3
SCHEMBL673282 0.82 LMNA (0.43) CA2CA1
SCHEMBL3837591 0.80 MGLL (0.41) MGLL
SCHEMBL8613201 0.77 ESR1 (0.54) CA2CA1TSHRCA4CA5A
SCHEMBL8612473 0.77 ESR1 (0.54) CA2CA1TSHRCA4CA5A
SCHEMBL8612867 0.77 ESR1 (0.54) CA2CA1TSHRCA4CA5A
SCHEMBL1353127 0.77 ESR1 (0.54) CA2CA1TSHRCA4CA5A
SCHEMBL1353131 0.77 ESR1 (0.54) CA2CA1TSHRCA4CA5A
SCHEMBL1353222 0.77 ESR1 (0.54) CA2CA1TSHRCA4CA5A
SCHEMBL8617006 0.77 ESR1 (0.54) CA2CA1TSHRCA4CA5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230371363-A1 COMPOUNDS THAT CAN BE USED FOR STRUCTURING FUNCTIONAL LAYERS OF ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2023-11-16 US disclosed
US-20230371363-A1 COMPOUNDS THAT CAN BE USED FOR STRUCTURING FUNCTIONAL LAYERS OF ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2023-11-16 US disclosed
WO-2022069421-A1 COMPOUNDS THAT CAN BE USED FOR STRUCTURING FUNCTIONAL LAYERS OF ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2022-04-07 WO disclosed
EP-1348711-B1 LUMINESCENT ELEMENT AND DISPLAY CANON KK (JP) 2018-06-13 EP disclosed
EP-1889891-B1 Luminescence device and display apparatus CANON KK (JP) 2017-11-22 EP disclosed
US-20150076478-A1 LUMINESCENCE DEVICE AND DISPLAY APPARATUS CANON KK (JP) 2015-03-19 US disclosed
US-8920943-B2 Luminescence device and display apparatus CANON KABUSHIKI KAISHA (JP) 2014-12-30 US disclosed
US-7687155-B2 Comprises iridium complexes, coordination compounds; red phosphorescence; high efficiency CANON KABUSHIKI KAISHA (JP) 2010-03-30 US disclosed
US-20090184634-A1 LUMINESCENCE DEVICE AND DISPLAY APPARATUS CANON KABUSHIKI KAISHA (JP) 2009-07-23 US disclosed
US-7544426-B2 Comprises iridium complexes, coordination compounds; red phosphorescence; high efficiency CANON KABUSHIKI KAISHA (JP) 2009-06-09 US disclosed
US-7527879-B2 Luminescence device and display apparatus CANON KABUSHIKI KAISHA (JP) 2009-05-05 US disclosed
EP-1889891-A2 Luminescence device and display apparatus Canon Kabushiki Kaisha (JP) 2008-02-20 EP disclosed
EP-1881050-A2 Luminescence device and display apparatus Canon Kabushiki Kaisha (JP) 2008-01-23 EP disclosed
US-20070216294-A1 LUMINESCENCE DEVICE AND DISPLAY APPARATUS CANON KABUSHIKI KAISHA (JP) 2007-09-20 US disclosed
US-20070212570-A1 Comprises iridium complexes, coordination compounds; red phosphorescence; high efficiency CANON KABUSHIKI KAISHA (JP) 2007-09-13 US disclosed
US-7147935-B2 Such as tetrakis(1-(5-heptyloxyphenyl)isoquinoline-C2,N) (pu-dichloro) iridium (III); for red luminescence; graphic arts CANON KABUSHIKI KAISHA (JP) 2006-12-12 US disclosed
US-20060177694-A1 Comprises iridium complexes, coordination compounds; red phosphorescence; high efficiency CANON KABUSHIKI KAISHA (JP) 2006-08-10 US disclosed
CN-1474826-A Light emitting device and display ������������ʽ���� 2004-02-11 CN disclosed
EP-1348711-A1 LUMINESCENT ELEMENT AND DISPLAY CANON KABUSHIKI KAISHA (JP) 2003-10-01 EP disclosed
US-20030068526-A1 Such as tetrakis(1-(5-heptyloxyphenyl)isoquinoline-C2,N) (pu-dichloro) iridium (III); for red luminescence; graphic arts CANON KABUSHIKI KAISHA (JP) 2003-04-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060177694-A1 Comprises iridium complexes, coordination compounds; red phosphorescence; high efficiency AP3M1, MLEC, MLX MGLL 393/4885TRPV6 1002/4885ORAI1 1354/4885
US-20230371363-A1 COMPOUNDS THAT CAN BE USED FOR STRUCTURING FUNCTIONAL LAYERS OF ORGANIC ELECTROLUMINESCENT DEVICES EPCAM, SELE, CTCF MGLL 2579/4885TRPV6 170/4885ORAI1 1008/4885
US-20090184634-A1 LUMINESCENCE DEVICE AND DISPLAY APPARATUS SOD1, NLRP1, LUC7L2 MGLL 195/4885TRPV6 504/4885ORAI1 186/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.