SCHEMBL3838560

SCHEMBL3838560

CC(=CC(C=Cc1ccccc1)=Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.51
CYP3A4 P08684 3/20 0.49
KMT2A Q03164 3/20 0.49
TDP1 Q9NUW8 3/20 0.49
HSPD1 P10809 2/20 0.49
HSPE1 P61604 2/20 0.49
PKM P14618 2/20 0.49
F3 P13726 2/20 0.49
MEN1 O00255 2/20 0.49
MAPT P10636 2/20 0.49
MAOA P21397 2/20 0.49
MAOB P27338 2/20 0.49
NFKB1 P19838 1/20 0.49
RAB9A P51151 1/20 0.49
NFKB2 Q00653 1/20 0.49
RELA Q04206 1/20 0.49
ALDH2 P05091 1/20 0.49
CYP19A1 P11511 1/20 0.49
CYP1B1 Q16678 1/20 0.49
ESR1 P03372 6/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL186692 0.93 AKR1C3 (0.59) AKR1C3TDP1F3MAPTMAOB
SCHEMBL9577533 0.81 AKR1C3 (0.70) AKR1C3CYP3A4KMT2ATDP1MEN1
SCHEMBL7872182 0.81 MAPT (0.55) CYP3A4KMT2ATDP1HSPD1HSPE1
SCHEMBL1456939 0.80 AKR1C3 (0.59) AKR1C3CYP3A4KMT2ATDP1MEN1
SCHEMBL249834 0.77 AKR1C3 (0.54) AKR1C3CYP3A4KMT2ATDP1MEN1
SCHEMBL7849380 0.77 GLA (0.50) AKR1C3KMT2ATDP1F3MAPT
SCHEMBL3293108 0.76 AKR1C3 (0.41) AKR1C3CYP3A4KMT2ATDP1MEN1
SCHEMBL499104 0.76 CYP3A4 (0.53) CYP3A4KMT2ATDP1HSPD1HSPE1
SCHEMBL364235 0.75 AKR1C3 (0.53) AKR1C3KMT2ATDP1PKMMAPT
SCHEMBL4949600 0.75 GLA (0.49) AKR1C3KMT2ATDP1F3MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1449833-B1 BISIMIDE COMPOUND, ACID GENERATOR AND RESIST COMPOSITION EACH CONTAINING THE SAME, AND METHOD OF FORMING PATTERN FROM THE COMPOSITION WAKO PURE CHEM IND LTD (JP) 2009-09-09 EP disclosed
US-7374857-B2 Bismide compound, acid generator and resist composition each containing the same, and method of forming pattern from the composition WAKO PURE CHEMICAL INDUSTRIES LTD. (JP) 2008-05-20 US disclosed
US-20050038261-A1 Bismide compound, acid generator and resist composition each containing the same, and method of forming pattern from the composition WAKO PURE CHEMICAL INDUSTRIES LTD. (JP) 2005-02-17 US disclosed
EP-1449833-A1 BISIMIDE COMPOUND, ACID GENERATOR AND RESIST COMPOSITION EACH CONTAINING THE SAME, AND METHOD OF FORMING PATTERN FROM THE COMPOSITION Wako Pure Chemical Industries, Ltd. (JP) 2004-08-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050038261-A1 Bismide compound, acid generator and resist composition each containing the same, and method of forming pattern from the composition ASIC1, GAR1, RER1 AKR1C3 2095/4885CYP3A4 2399/4885KMT2A 1016/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.