Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.41 |
| ▸ | CTRB1 | P17538 | 4/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7175865 | 0.91 | SIGMAR1 (0.48) | SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7181583 | 0.89 | SIGMAR1 (0.46) | SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7183353 | 0.89 | SIGMAR1 (0.46) | SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7183358 | 0.87 | TRPA1 (0.45) | SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7192690 | 0.87 | TRPA1 (0.45) | SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9752209 | 0.84 | SIGMAR1 (0.54) | SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3 | |
| Iodide SCHEMBL931546 | 0.84 | SIGMAR1 (0.54) | SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3 | |
| Bromide SCHEMBL515994 | 0.84 | SIGMAR1 (0.54) | SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3 | |
| Fluoride Ion SCHEMBL4615583 | 0.84 | SIGMAR1 (0.54) | SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3 | |
| Fluoride Ion SCHEMBL28882550 | 0.84 | SIGMAR1 (0.54) | SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2718448-A2 | METHODS FOR TREATING LIGNOCELLULOSIC MATERIAL | Syngenta Participations AG (CH) | 2014-04-16 | — | — | EP | disclosed |
| WO-2012168410-A2 | METHODS FOR TREATING LIGNOCELLULOSIC MATERIAL | SYNGENTA PARTICIPATIONS AG (CH) | 2012-12-13 | — | — | WO | disclosed |
| EP-2439208-A1 | Method of preparing organometallic compounds | Rohm and Haas Company (US) | 2012-04-11 | — | — | EP | disclosed |
| US-8101787-B2 | Method of preparing organometallic compounds | ROHM AND HAAS COMPANY (US) | 2012-01-24 | — | — | US | disclosed |
| US-20110172452-A1 | Method of Preparing Organometallic Compounds | ROHM AND HAAS COMPANY (US) | 2011-07-14 | — | — | US | disclosed |
| US-7939684-B2 | Method of preparing organometallic compounds | ROHM AND HAAS COMPANY (US) | 2011-05-10 | — | — | US | disclosed |
| US-7919638-B2 | Method of preparing organometallic compounds | ROHM AND HAAS COMPANY (US) | 2011-04-05 | — | — | US | disclosed |
| US-20100185003-A1 | Method of Preparing Organometallic Compounds | ROHM AND HAAS COMPANY (US) | 2010-07-22 | — | — | US | disclosed |
| US-20100185002-A1 | Method of Preparing Organometallic Compounds | ROHM AND HAAS COMPANY (US) | 2010-07-22 | — | — | US | disclosed |
| US-7659414-B2 | Method of preparing organometallic compounds | ROHM AND HAAS COMPANY (US) | 2010-02-09 | — | — | US | disclosed |
| EP-2020258-A2 | Method Of Preparing Organometallic Compounds | Rohm and Haas Company (US) | 2009-02-04 | — | — | EP | disclosed |
| US-20090023940-A1 | Method of preparing organometallic compounds | ROHM AND HAAS COMPANY | 2009-01-22 | — | — | US | disclosed |