Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 5/20 | 0.46 |
| ▸ | TUBB | P07437 | 5/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 5/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 5/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 5/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 5/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 5/20 | 0.46 |
| ▸ | TUBB2A | Q13885 | 5/20 | 0.46 |
| ▸ | TUBB8 | Q3ZCM7 | 5/20 | 0.46 |
| ▸ | TUBA3E | Q6PEY2 | 5/20 | 0.46 |
| ▸ | TUBA1A | Q71U36 | 5/20 | 0.46 |
| ▸ | TUBA1C | Q9BQE3 | 5/20 | 0.46 |
| ▸ | TUBB6 | Q9BUF5 | 5/20 | 0.46 |
| ▸ | TUBB2B | Q9BVA1 | 5/20 | 0.46 |
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3837549 | 0.86 | TUBB4A (0.38) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL3835082 | 0.84 | HTR2A (0.39) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL3839592 | 0.83 | TUBB4A (0.39) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL3839514 | 0.82 | TUBB4A (0.36) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL3835938 | 0.81 | PPARG (0.41) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL28458695 | 0.77 | TUBB4A (0.57) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL3835919 | 0.75 | HTR2A (0.41) | HTR2AHTR2CSMN1; SMN2POLB | |
| SCHEMBL3840372 | 0.74 | PPARG (0.35) | HTR2AHTR2CLMNAALDH1A1PPARG | |
| SCHEMBL3839247 | 0.71 | PPARG (0.35) | HTR2AHTR2CALDH1A1PPARGKDM4E | |
| SCHEMBL8846952 | 0.69 | CHRNB2 (0.49) | MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1791537-B1 | 3-ARYLTHIOINDOLE-2-CARBOXAMIDE DERIVATIVES AND ANALOGS THEREOF AS INHIBITORS OF CASEIN KINASE I | AVENTIS PHARMA INC (US) | 2009-10-14 | — | — | EP | claimed |