Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 12/20 | 0.56 |
| ▸ | ITGAV | P06756 | 12/20 | 0.56 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.40 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.35 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.35 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.35 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL384017 | 0.89 | ITGB3 (0.56) | ITGB3ITGAVITGA2BADRA2AADRA2B | |
| SCHEMBL382288 | 0.81 | ITGB3 (0.49) | ITGB3ITGAVITGA2BADRA2AADRA2B | |
| SCHEMBL382698 | 0.80 | ITGB3 (0.53) | ITGB3ITGAVITGA2B | |
| SCHEMBL6793131 | 0.80 | ITGB3 (0.59) | ITGB3ITGAVITGA2B | |
| SCHEMBL6793124 | 0.80 | ITGB3 (0.71) | ITGB3ITGAVITGA2B | |
| SCHEMBL383018 | 0.79 | ITGB3 (0.59) | ITGB3ITGAVITGA2BSMYD3 | |
| SCHEMBL383017 | 0.79 | ITGB3 (0.70) | ITGB3ITGAVITGA2B | |
| SCHEMBL31444440 | 0.79 | ITGB3 (0.50) | ITGB3ITGAVITGA2BL3MBTL3L3MBTL1 | |
| SCHEMBL382289 | 0.79 | ITGB3 (0.49) | ITGB3ITGAVITGA2BADRA2AADRA2B | |
| SCHEMBL6797331 | 0.79 | ITGB3 (0.58) | ITGB3ITGAVITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | claimed |