Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 10/20 | 0.53 |
| ▸ | ITGAV | P06756 | 10/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.53 |
| ▸ | PTGIR | P43119 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL382838 | 0.93 | PTGIR (0.53) | ITGB3ITGAVITGA2BPTGIRALDH1A1 | |
| SCHEMBL384017 | 0.80 | ITGB3 (0.56) | ITGB3ITGAVITGA2B | |
| SCHEMBL384016 | 0.80 | ITGB3 (0.56) | ITGB3ITGAVITGA2B | |
| SCHEMBL382510 | 0.78 | NOS2 (0.51) | ALDH1A1HSP90AA1MAPTMEN1KMT2A | |
| SCHEMBL6793124 | 0.76 | ITGB3 (0.71) | ITGB3ITGAVITGA2B | |
| SCHEMBL6797761 | 0.76 | ITGB3 (0.65) | ITGB3ITGAVITGA2B | |
| SCHEMBL383017 | 0.76 | ITGB3 (0.70) | ITGB3ITGAVITGA2B | |
| SCHEMBL6793131 | 0.74 | ITGB3 (0.59) | ITGB3ITGAVITGA2B | |
| SCHEMBL6797778 | 0.74 | ITGB3 (0.55) | ITGB3ITGAVITGA2B | |
| Hydrochloric Acid SCHEMBL2514818 | 0.74 | MEN1 (0.50) | ALDH1A1HSP90AA1MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | disclosed |
| US-6420558-B1 | COMPOUNDS WITH AMIDINE GROUPS ANTAGONISTIC ACTIVITY, CELL ADHESION INHIBITORY ACTIVITY, HUMAN PLATELET AGGREGATION INHIBITORY ACTIVITY, AND THERAPEUTIC AGENTS | MEIJI SEIKA KAISHA, LTD. (JP) | 2002-07-16 | — | — | US | disclosed |
| EP-1074543-A1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA KAISHA LTD. (JP) | 2001-02-07 | — | — | EP | disclosed |