Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 10/20 | 0.56 |
| ▸ | ITGAV | P06756 | 10/20 | 0.56 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.40 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL384016 | 0.89 | ITGB3 (0.56) | ITGB3ITGAVITGA2BADRA2AADRA2B | |
| SCHEMBL31444440 | 0.88 | ITGB3 (0.50) | ITGB3ITGAVITGA2BCNR1CNR2 | |
| SCHEMBL382289 | 0.81 | ITGB3 (0.49) | ITGB3ITGAVITGA2BADRA2AADRA2B | |
| SCHEMBL383018 | 0.81 | ITGB3 (0.59) | ITGB3ITGAVITGA2B | |
| SCHEMBL383017 | 0.81 | ITGB3 (0.70) | ITGB3ITGAVITGA2B | |
| SCHEMBL382698 | 0.80 | ITGB3 (0.53) | ITGB3ITGAVITGA2B | |
| SCHEMBL6793124 | 0.80 | ITGB3 (0.71) | ITGB3ITGAVITGA2B | |
| SCHEMBL6793131 | 0.80 | ITGB3 (0.59) | ITGB3ITGAVITGA2B | |
| SCHEMBL382288 | 0.79 | ITGB3 (0.49) | ITGB3ITGAVITGA2BADRA2AADRA2B | |
| SCHEMBL6797319 | 0.79 | ITGB3 (0.64) | ITGB3ITGAVITGA2BCNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | claimed |