Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.32 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | CPT2 | P23786 | 1/20 | 0.32 |
| ▸ | CPT1A | P50416 | 1/20 | 0.32 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3842934 | 0.89 | SLC2A1 (0.38) | MAPK1L3MBTL1SMPD1PPARGPPARA | |
| SCHEMBL3840687 | 0.81 | POLB (0.36) | MAPK1CYP2D6PPARGPPARAGAA | |
| SCHEMBL3284699 | 0.80 | THRA (0.36) | SMPD1CYP2D6PPARGPPARACYSLTR2 | |
| SCHEMBL3844501 | 0.80 | KDM4E (0.35) | MAPK1CYP2D6PPARGPPARAGAA | |
| SCHEMBL3291240 | 0.79 | PPARA (0.35) | SMPD1CYP2D6PPARGPPARAMAOA | |
| SCHEMBL3287365 | 0.79 | PPARA (0.36) | SMPD1PPARGPPARACYSLTR2CYSLTR1 | |
| SCHEMBL3286825 | 0.77 | PPARA (0.36) | SMPD1PPARGPPARASMN1; SMN2MAOA | |
| SCHEMBL3845612 | 0.74 | PPARA (0.42) | PPARGPPARA | |
| SCHEMBL3841106 | 0.72 | THRA (0.38) | SMPD1CYSLTR2CYSLTR1 | |
| SCHEMBL3844113 | 0.72 | ALOX5 (0.36) | PPARGPPARACYSLTR2CYSLTR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1856065-B1 | 1,2,4-TRIAZINE DERIVATIVES, PREPARATION AND USE THEREOF IN HUMAN THERAPY | PF MEDICAMENT (FR) | 2009-11-11 | — | — | EP | claimed |