Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3841459 | 0.92 | PKM (0.34) | EPHX2PLA2G4AALDH1A1TSHRMAPK1 | |
| SCHEMBL3842276 | 0.91 | TP53 (0.39) | PLA2G4AALDH1A1TSHRMAPK1TP53 | |
| SCHEMBL3849934 | 0.90 | PPARG (0.38) | PLA2G4AALDH1A1TSHRMAPK1TP53 | |
| SCHEMBL3846393 | 0.90 | TP53 (0.39) | PLA2G4AALDH1A1TSHRMAPK1TP53 | |
| SCHEMBL3844301 | 0.90 | PPARG (0.39) | — | |
| SCHEMBL3841422 | 0.87 | PKM (0.34) | EPHX2ALDH1A1TSHRMAPK1L3MBTL1 | |
| SCHEMBL3284582 | 0.85 | PPARA (0.39) | ALDH1A1TSHRMAPK1L3MBTL1POLB | |
| SCHEMBL3841118 | 0.85 | PPARA (0.40) | — | |
| SCHEMBL3844889 | 0.84 | PPARA (0.42) | — | |
| SCHEMBL3842289 | 0.84 | PPARG (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1856065-B1 | 1,2,4-TRIAZINE DERIVATIVES, PREPARATION AND USE THEREOF IN HUMAN THERAPY | PF MEDICAMENT (FR) | 2009-11-11 | — | — | EP | claimed |