Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | CDK4 | P11802 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CCND1 | P24385 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | SLC22A2 | O15244 | 2/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10128232 | 0.87 | ALDH1A1 (0.52) | ALDH1A1MEN1KMT2ANOTUMUSP2 | |
| SCHEMBL8999008 | 0.79 | MAOA (0.40) | ALDH1A1MEN1KMT2ANOTUMUSP2 | |
| SCHEMBL29946500 | 0.78 | MEN1 (0.50) | ALDH1A1MEN1KMT2ANOTUMSMN1; SMN2 | |
| SCHEMBL678115 | 0.78 | MEN1 (0.50) | ALDH1A1MEN1KMT2ANOTUMSMN1; SMN2 | |
| SCHEMBL13663474 | 0.78 | MEN1 (0.45) | ALDH1A1MEN1KMT2ANOTUMUSP2 | |
| SCHEMBL2604390 | 0.78 | MAOA (0.52) | ALDH1A1MEN1KMT2ANOTUMUSP2 | |
| SCHEMBL677619 | 0.74 | MEN1 (0.50) | ALDH1A1MEN1KMT2ANOTUMUSP2 | |
| SCHEMBL21120469 | 0.74 | MEN1 (0.47) | ALDH1A1MEN1KMT2ANOTUMSMN1; SMN2 | |
| SCHEMBL29699544 | 0.71 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2ANOTUMUSP2 | |
| SCHEMBL159025 | 0.71 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2ANOTUMUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2111403-A1 | TRIAZABENZO[E]AZULENE DERIVATIVES FOR THE TREATMENT OF TUMORS | Merck Patent GmbH (DE) | 2009-10-28 | — | — | EP | disclosed |
| WO-2008052628-A1 | TRIAZABENZO[E]AZULENE DERIVATIVES FOR THE TREATMENT OF TUMORS | MERCK PATENT GMBH (DE) | 2008-05-08 | — | — | WO | disclosed |