Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 3/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.40 |
| ▸ | HRH1 | P35367 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD1 | P21728 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | DRD5 | P21918 | 1/20 | 0.39 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL975897 | 0.81 | MAOA (0.52) | MAOAHTR2AADRA2AADRA2BADRA2C | |
| SCHEMBL29351597 | 0.81 | MAOA (0.52) | MAOAHTR2AADRA2AADRA2BADRA2C | |
| Iodide SCHEMBL11862710 | 0.79 | MAOA (0.50) | MAOAHTR2AADRA2AADRA2BADRA2C | |
| SCHEMBL29735917 | 0.79 | MAOA (0.50) | MAOAHTR2AADRA2AADRA2BADRA2C | |
| SCHEMBL3841522 | 0.79 | ALDH1A1 (0.46) | HTR2AADRA2BADRA2CSLC6A2HTR2C | |
| SCHEMBL3957285 | 0.76 | ALDH1A1 (0.42) | MAOAHTR2AADRA2AADRA2BADRA2C | |
| SCHEMBL9833997 | 0.75 | ADRA2B (0.51) | HTR2AADRA2AADRA2BADRA2CSLC6A2 | |
| SCHEMBL4442728 | 0.74 | MAOA (0.40) | MAOAHTR2AADRA2AADRA2BADRA2C | |
| SCHEMBL12723261 | 0.74 | MAOA (0.45) | MAOAHTR2AADRA2AADRA2BADRA2C | |
| SCHEMBL10460338 | 0.74 | CYP1A2 (0.58) | MAOAHTR2AADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118048633-A | Method for electrochemically synthesizing trifluoro methylthio oxindole | 上海电力大学 | 2024-05-17 | — | — | CN | claimed |
| CN-118048633-A | Method for electrochemically synthesizing trifluoro methylthio oxindole | 上海电力大学 | 2024-05-17 | — | — | CN | disclosed |
| CN-118048633-A | Method for electrochemically synthesizing trifluoro methylthio oxindole | 上海电力大学 | 2024-05-17 | — | — | CN | disclosed |
| CN-118048633-A | Method for electrochemically synthesizing trifluoro methylthio oxindole | 上海电力大学 | 2024-05-17 | — | — | CN | disclosed |
| US-5556874-A | ENZYME INHIBITORS AS ANTICARCINOGENIC AGENTS | WARNER LAMBERT COMPANY (US) | 1996-09-17 | — | — | US | disclosed |
| US-5464861-A | Anticarcinogenic agents | WARNER-LAMBERT (US) | 1995-11-07 | — | — | US | disclosed |
| EP-0654024-A1 | 2-THIOINDOLES (SELENOINDOLES) AND RELATED DISULFIDES (SELENIDES) WHICH INHIBIT PROTEIN TYROSINE KINASES AND WHICH HAVE ANTITUMOR PROPERTIES | WARNER-LAMBERT COMPANY (US) | 1995-05-24 | — | — | EP | disclosed |
| WO-1994003427-A1 | 2-THIOINDOLES (SELENOINDOLES) AND RELATED DISULFIDES (SELENIDES) WHICH INHIBIT PROTEIN TYROSINE KINASES AND WHICH HAVE ANTITUMOR PROPERTIES | WARNER-LAMBERT COMPANY (US) | 1994-02-17 | — | — | WO | disclosed |
| US-5030646-A | Treatment of diseases resulting from disfunction of seretoninergic system | ADIR ET COMPAGNIE (FR) | 1991-07-09 | — | — | US | disclosed |