SCHEMBL22644196

SCHEMBL22644196

Oc1ccc([C@]23CC4CC(C[C@H](C4)C2)C3)cc1

nearest known ligand 0.63

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.63
ALDH1A1 P00352 3/20 0.63
MEN1 O00255 3/20 0.62
KMT2A Q03164 3/20 0.62
GAA P10253 3/20 0.62
POLB P06746 1/20 0.62
GFER P55789 1/20 0.62
EPHX2 P34913 7/20 0.56
NPC1 O15118 1/20 0.53
MAPT P10636 2/20 0.50
RAB9A P51151 1/20 0.49
ESR1 P03372 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.47
XBP1 P17861 1/20 0.47
CNR2 P34972 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24559531 1.00 LMNA (0.63) LMNAALDH1A1MEN1KMT2AGAA
SCHEMBL345588 1.00 LMNA (0.63) LMNAALDH1A1MEN1KMT2AGAA
SCHEMBL20789695 0.91 LMNA (0.50) LMNAALDH1A1MEN1KMT2AGAA
SCHEMBL10296837 0.89 ALDH1A1 (0.52) LMNAALDH1A1MEN1KMT2AGAA
SCHEMBL2763437 0.88 LMNA (0.77) LMNAALDH1A1MEN1KMT2AGAA
SCHEMBL649556 0.87 ESR1 (0.60) LMNAALDH1A1MEN1KMT2AGAA
SCHEMBL16364512 0.87 ESR1 (0.60) LMNAALDH1A1MEN1KMT2AGAA
SCHEMBL20648576 0.86 MEN1 (0.49) LMNAALDH1A1MEN1KMT2AGAA
SCHEMBL28789384 0.85 ESR1 (0.58) LMNAALDH1A1MEN1KMT2AGAA
SCHEMBL17660048 0.85 EPHX2 (0.47) LMNAALDH1A1MEN1KMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12240857-B2 Adamantane derivatives for the treatment of filovirus infection ARISAN THERAPEUTICS INC. (US) 2025-03-04 US disclosed
US-11844270-B2 Compound and organic light emitting device including the same LG DISPLAY CO., LTD. (KR) 2023-12-12 US disclosed
US-11844270-B2 Compound and organic light emitting device including the same LG DISPLAY CO., LTD. (KR) 2023-12-12 US disclosed
US-20230363261-A1 LIGHT EMITTING DIODE AND DISPLAY DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-09 US disclosed
US-20230363261-A1 LIGHT EMITTING DIODE AND DISPLAY DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-09 US disclosed
US-11744147-B2 Light emitting diode and display device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-08-29 US disclosed
US-11744147-B2 Light emitting diode and display device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-08-29 US disclosed
US-20230157155-A1 LIGHT EMITTING DEVICE AND AMINE COMPOUND FOR LIGHT EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-05-18 US disclosed
US-20230157155-A1 LIGHT EMITTING DEVICE AND AMINE COMPOUND FOR LIGHT EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-05-18 US disclosed
US-20230141913-A2 PHENOXY(HETERO)ARYL ETHERS OF ANTIPROLIFERACTIVE ACTIVITY Xeniopro GmbH (DE) 2023-05-11 US disclosed
US-20120022080-A1 Plasminogen Activator Inhibitor-1 Inhibitor RENASCIENCE CO., LTD. (JP) 2012-01-26 US disclosed
US-7879530-B2 Antireflective coating composition, antireflective coating, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2011-02-01 US disclosed
US-7879530-B2 Antireflective coating composition, antireflective coating, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2011-02-01 US disclosed
US-7749678-B2 contains sulfonium compound; improved line edge roughness and pattern profile, and contrast of sensitivity and dissolution in extreme ultraviolet exposure FUJIFILM CORPORATION (JP) 2010-07-06 US disclosed
US-7749678-B2 contains sulfonium compound; improved line edge roughness and pattern profile, and contrast of sensitivity and dissolution in extreme ultraviolet exposure FUJIFILM CORPORATION (JP) 2010-07-06 US disclosed
US-20100151381-A1 ANTIREFLECTIVE COATING COMPOSITION, ANTIREFLECTIVE COATING , AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-06-17 US disclosed
US-20100151381-A1 ANTIREFLECTIVE COATING COMPOSITION, ANTIREFLECTIVE COATING , AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-06-17 US disclosed
US-20090087799-A1 ANTIREFLECTIVE COATING COMPOSITION, ANTIREFLECTIVE COATING, AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2009-04-02 US disclosed
US-20090087799-A1 ANTIREFLECTIVE COATING COMPOSITION, ANTIREFLECTIVE COATING, AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2009-04-02 US disclosed
EP-1764647-A2 Positive resist composition for immersion exposure and pattern-forming method using the same FUJIFILM Corporation (JP) 2007-03-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11844270-B2 Compound and organic light emitting device including the same TMEM109, CRY1, VDAC1 LMNA 3142/4885ALDH1A1 54/4885MEN1 1603/4885
US-12240857-B2 Adamantane derivatives for the treatment of filovirus infection IFNAR1, MEP1B, MEP1A LMNA 867/4885ALDH1A1 652/4885MEN1 1731/4885
US-20120022080-A1 Plasminogen Activator Inhibitor-1 Inhibitor SERPINE1, SERPINC1, SERPINB1 LMNA 482/4885ALDH1A1 1450/4885MEN1 844/4885
US-11744147-B2 Light emitting diode and display device including the same ALDH1A2, STRA6, DCX LMNA 3039/4885ALDH1A1 96/4885MEN1 3856/4885
US-20230141913-A2 PHENOXY(HETERO)ARYL ETHERS OF ANTIPROLIFERACTIVE ACTIVITY AHR, MUSK, TYR LMNA 2488/4885ALDH1A1 1806/4885MEN1 4794/4885
US-20230363261-A1 LIGHT EMITTING DIODE AND DISPLAY DEVICE INCLUDING THE SAME ALDH1A2, STRA6, DCX LMNA 3039/4885ALDH1A1 96/4885MEN1 3856/4885
US-20230157155-A1 LIGHT EMITTING DEVICE AND AMINE COMPOUND FOR LIGHT EMITTING DEVICE CRY1, SLC1A2, CHRM1 LMNA 2290/4885ALDH1A1 12/4885MEN1 463/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.