SCHEMBL649556

SCHEMBL649556

Oc1ccc(C23CC4CC(C2)CC(c2ccc(O)cc2)(C4)C3)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.60
ALDH1A1 P00352 3/20 0.56
PGR P06401 5/20 0.51
LMNA P02545 3/20 0.51
GRIN2D O15399 1/20 0.50
GRIN3B O60391 1/20 0.50
GRIN1 Q05586 1/20 0.50
GRIN2A Q12879 1/20 0.50
GRIN2B Q13224 1/20 0.50
GRIN2C Q14957 1/20 0.50
GRIN3A Q8TCU5 1/20 0.50
NPC1 O15118 1/20 0.49
RAB9A P51151 1/20 0.49
MEN1 O00255 4/20 0.48
KMT2A Q03164 4/20 0.48
POLB P06746 1/20 0.48
GAA P10253 1/20 0.48
GFER P55789 1/20 0.48
RAD52 P43351 1/20 0.46
HTT P42858 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16364512 1.00 ESR1 (0.60) ESR1ALDH1A1PGRLMNAGRIN2D
SCHEMBL28789384 0.98 ESR1 (0.58) ESR1ALDH1A1PGRLMNAGRIN2D
SCHEMBL19150636 0.93 GRIN2D (0.62) ESR1ALDH1A1PGRLMNAGRIN2D
SCHEMBL17370938 0.91 MEN1 (0.58) ESR1ALDH1A1LMNAMEN1KMT2A
SCHEMBL3848262 0.90 ESR1 (0.52) ESR1ALDH1A1PGRLMNAGRIN2D
SCHEMBL3843125 0.89 ESR1 (0.52) ESR1ALDH1A1PGRLMNAGRIN2D
SCHEMBL3844410 0.88 ESR1 (0.51) ESR1ALDH1A1PGRLMNAGRIN2D
SCHEMBL24559531 0.87 LMNA (0.63) ESR1ALDH1A1LMNANPC1RAB9A
SCHEMBL345588 0.87 LMNA (0.63) ESR1ALDH1A1LMNANPC1RAB9A
SCHEMBL22644196 0.87 LMNA (0.63) ESR1ALDH1A1LMNANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 670 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117467249-A Anti-irradiation fruit fresh-keeping film and preparation method thereof 台州鸿博辐照科技有限公司 2024-01-30 CN claimed
CN-114276530-A Intermittent phosgene interface method preparation process of polycarbonate and application thereof 深圳市德力塑化工科技有限公司 2022-04-05 CN claimed
US-10934455-B2 Polysilsesquioxane resin composition for flexible substrate LTC CO., LTD. 2021-03-02 US claimed
EP-3078711-B1 RESIN COMPOSITION HAVING IMPROVED HAZE AND LIGHT TRANSMITTANCE AND PROCESS FOR PREPARING THE SAME CHINA PETROLEUM & CHEM CORP (CN) 2020-06-10 EP claimed
US-20190023942-A1 POLYSILSESQUIOXANE RESIN COMPOSITION FOR FLEXIBLE SUBSTRATE LTC CO., LTD. (KR) 2019-01-24 US claimed
CN-105418885-B UV-cured polyurethane acrylate and preparation method thereof 深圳砺剑博纳科技有限公司 2018-11-09 CN claimed
CN-105440245-B Ultraviolet-curing paint and preparation method thereof 贾学明 2018-05-22 CN claimed
US-9834675-B2 Resin composition having improved haze and light transmittance and process for preparing the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2017-12-05 US claimed
EP-2447299-B1 POLYCARBONATE COPOLYMER, COATING LIQUID USING SAME, AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY IDEMITSU KOSAN CO (JP) 2017-11-29 EP claimed
US-20160297965-A1 Resin Composition Having Improved Haze and Light Transmittance and Process for Preparing the Same BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2016-10-13 US claimed
US-6720460-B2 FORMING HEAT RESISTANT, MECHANICAL STRENGTH POLYMER ADDITIVES; ACID CATALYZED REACTION OF ADAMANTANE DIOL OR TRIOL WITH PHENOLIC DERIVATIVE HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2004-04-13 US claimed
US-20040049004-A1 Process for manufacturing an alpha-dihydroxy derivative and epoxy resins prepared therefrom THE DOW CHEMICAL COMPANY 2004-03-11 US claimed
US-6646102-B2 Epoxidizing an alpha - halohydrin intermediate produced from a halide substitution of an alpha -dihydroxy derivative which has been obtained by a dihydroxylation reaction of an aryl allyl ether, oxidation catalysts DOW GLOBAL TECHNOLOGIES INC. 2003-11-11 US claimed
US-20030187307-A1 Hydroxyphenyl adamantanes and process for the production of the same HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2003-10-02 US claimed
EP-1336597-A1 Hydroxyphenyl adamantanes and process for the production of the same Honshu Chemical Industry Co., Ltd. (JP) 2003-08-20 EP claimed
EP-1327260-A2 SIMPLIFIED METHOD TO PRODUCE NANOPOROUS SILICON-BASED FILMS Honeywell International Inc. (US) 2003-07-16 EP claimed
US-20030105268-A1 Process for manufacturing an alpha-dihydroxy derivative and epoxy resins prepared therefrom DOW GLOBAL TECHNOLOGIES INC. 2003-06-05 US claimed
US-20030077918-A1 Simplified method to produce nanoporous silicon-based films WU HUI-JUNG (US) 2003-04-24 US claimed
US-6495479-B1 COATING WITH SUCH AS TETRAACETOXYSILANE AND A POROGEN, AGING OR CONDENSING IN PRESENCE OF WATER AND HEATING THE GELLED FILM HONEYWELL INTERNATIONAL, INC. 2002-12-17 US claimed
WO-2001086709-A2 SIMPLIFIED METHOD TO PRODUCE NANOPOROUS SILICON-BASED FILMS HONEYWELL INTERNATIONAL INC. (US) 2001-11-15 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030187307-A1 Hydroxyphenyl adamantanes and process for the production of the same CYP8B1, DHPS, P4HA1 ESR1 4719/4885ALDH1A1 118/4885PGR 4240/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.