Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.38 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.38 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.38 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.38 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.38 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.38 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.38 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.38 |
| ▸ | CACNG1 | Q06432 | 1/20 | 0.38 |
| ▸ | CACNB2 | Q08289 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL284469 | 0.85 | TSHR (0.41) | TDP1TSHRSMN1; SMN2ACHECYP3A4 | |
| SCHEMBL196533 | 0.85 | ACHE (0.46) | TSHRSMN1; SMN2ACHECYP3A4ALDH1A1 | |
| SCHEMBL1476156 | 0.85 | TSHR (0.41) | TDP1TSHRSMN1; SMN2ACHECYP3A4 | |
| SCHEMBL1228376 | 0.85 | ACHE (0.46) | TSHRSMN1; SMN2ACHECYP3A4ALDH1A1 | |
| SCHEMBL712409 | 0.84 | TSHR (0.42) | TDP1TSHRSMN1; SMN2ACHECYP3A4 | |
| SCHEMBL1180196 | 0.79 | GAA (0.41) | TDP1TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL30823619 | 0.79 | GAA (0.41) | TDP1TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL10560069 | 0.79 | CYP1A2 (0.50) | TSHRACHECYP3A4ALDH1A1CACNB4 | |
| SCHEMBL3840820 | 0.77 | TDP1 (0.53) | TDP1TSHRSMN1; SMN2CYP3A4ALDH1A1 | |
| SCHEMBL1453562 | 0.76 | TSHR (0.43) | TSHRSMN1; SMN2ACHECYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1848691-B1 | PROCESS FOR THE PREPARATION OF INDOLONE DERIVATIVE | ALEMBIC LTD (IN) | 2009-11-11 | — | — | EP | claimed |
| EP-1848691-A1 | PROCESS FOR THE PREPARATION OF INDOLONE DERIVATIVE | Alembic Limited (IN) | 2007-10-31 | — | — | EP | disclosed |
| WO-2006123356-A1 | PROCESS FOR THE PREPARATION OF INDOLONE DERIVATIVE | ALEMBIC LIMITED (IN) | 2006-11-23 | — | — | WO | disclosed |