Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 10/20 | 0.39 |
| ▸ | PPARA | Q07869 | 9/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 5/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.35 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3842005 | 0.91 | PPARG (0.42) | PPARGPPARAPPARDS1PR4S1PR1 | |
| SCHEMBL3847191 | 0.91 | PPARG (0.42) | PPARGPPARAPPARDS1PR4S1PR1 | |
| SCHEMBL3842859 | 0.91 | PPARA (0.42) | PPARGPPARAPPARDS1PR4S1PR1 | |
| SCHEMBL3841197 | 0.90 | PPARA (0.48) | PPARGPPARAPPARD | |
| SCHEMBL3849916 | 0.87 | PPARA (0.41) | PPARGPPARACNR1ACHECNR2 | |
| SCHEMBL3848677 | 0.86 | PPARG (0.41) | PPARGPPARACNR1ACHECNR2 | |
| SCHEMBL3846291 | 0.84 | PLA2G4B (0.40) | PPARGPPARAPLA2G4BSMPD1KMT2A | |
| SCHEMBL3292871 | 0.84 | PPARA (0.44) | PPARGPPARACNR1ACHECNR2 | |
| SCHEMBL3845248 | 0.83 | PLA2G4B (0.40) | PPARGPPARAPLA2G4BSMPD1KMT2A | |
| SCHEMBL3844865 | 0.83 | PPARA (0.48) | PPARGPPARACNR1CNR2PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1856065-B1 | 1,2,4-TRIAZINE DERIVATIVES, PREPARATION AND USE THEREOF IN HUMAN THERAPY | PF MEDICAMENT (FR) | 2009-11-11 | — | — | EP | claimed |
| US-20080167313-A1 | 1,2,4-Triazine Derivatives, Preparation and Use Thereof in Human Therapy | PIERRE FABRE MEDICAMENT (FR) | 2008-07-10 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080167313-A1 | 1,2,4-Triazine Derivatives, Preparation and Use Thereof in Human Therapy | CBR3, NOX3, RTN3 | PPARG 2530/4885PPARA 3384/4885CNR1 119/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.