Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 11/20 | 0.41 |
| ▸ | PPARG | P37231 | 9/20 | 0.41 |
| ▸ | PPARD | Q03181 | 6/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3841403 | 0.92 | PPARA (0.43) | PPARAPPARGPPARD | |
| SCHEMBL3840282 | 0.92 | PPARA (0.49) | PPARAPPARGPPARD | |
| SCHEMBL3842218 | 0.90 | PPARA (0.36) | PPARAPPARGPPARDKDM4EALDH1A1 | |
| SCHEMBL3848677 | 0.88 | PPARG (0.41) | PPARAPPARGPPARDCNR1ACHE | |
| SCHEMBL3842292 | 0.87 | PPARG (0.39) | PPARAPPARGPPARDCNR1ACHE | |
| SCHEMBL3287354 | 0.86 | PPARA (0.40) | PPARAPPARGPPARDCNR1ACHE | |
| SCHEMBL3841446 | 0.85 | PPARA (0.51) | PPARAPPARGPPARD | |
| SCHEMBL3840790 | 0.85 | PPARA (0.46) | PPARAPPARGPPARDCNR1CNR2 | |
| SCHEMBL3848673 | 0.85 | PPARA (0.44) | PPARAPPARGPPARDCNR1CNR2 | |
| SCHEMBL3851244 | 0.83 | PPARA (0.43) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1856065-B1 | 1,2,4-TRIAZINE DERIVATIVES, PREPARATION AND USE THEREOF IN HUMAN THERAPY | PF MEDICAMENT (FR) | 2009-11-11 | — | — | EP | claimed |