SCHEMBL384254

SCHEMBL384254

CC(C)(C)OOC(=O)C12CCC(CC1)C2

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.41
HTT P42858 2/20 0.41
NPSR1 Q6W5P4 1/20 0.41
CYP17A1 P05093 1/20 0.31
CYP19A1 P11511 1/20 0.31
SCN1A P35498 1/20 0.31
SCN2A Q99250 1/20 0.31
SCN3A Q9NY46 1/20 0.31
TSHR P16473 1/20 0.30
HSD17B10 Q99714 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL216423 0.81 ALDH1A1 (0.43) ALDH1A1HTTNPSR1CYP17A1CYP19A1
SCHEMBL19452730 0.81 CYP17A1 (0.45) ALDH1A1HTTNPSR1CYP17A1CYP19A1
SCHEMBL11884387 0.79 NPSR1 (0.36) ALDH1A1HTTNPSR1SCN1ASCN2A
SCHEMBL19452732 0.76 CYP17A1 (0.38) ALDH1A1HTTNPSR1CYP17A1CYP19A1
SCHEMBL19452729 0.76 CYP17A1 (0.38) ALDH1A1HTTNPSR1CYP17A1CYP19A1
SCHEMBL3704482 0.75 ALDH1A1 (0.42) ALDH1A1HTTNPSR1SCN1ASCN2A
SCHEMBL2515948 0.74 ALDH1A1 (0.38) ALDH1A1HTTNPSR1SCN1ASCN2A
SCHEMBL7600486 0.72 ALDH1A1 (0.37) ALDH1A1HTTNPSR1SCN1ASCN2A
SCHEMBL1409283 0.72 ALDH1A1 (0.39) ALDH1A1HTTNPSR1CYP17A1CYP19A1
SCHEMBL1699800 0.71 ALDH1A1 (0.36) ALDH1A1HTTNPSR1SCN1ASCN2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1853426-B1 MULTILAYER STRUCTURES BOREALIS TECH OY (FI) 2015-11-04 EP disclosed
EP-2220133-B1 POLYPROPYLENE COPOLYMER BOREALIS TECH OY (FI) 2012-01-25 EP disclosed
US-20100292410-A1 Polypropylene Copolymer BOREALIS TECHNOLOGY OY (FI) 2010-11-18 US disclosed
US-20100280206-A1 POLYETHYLENE COPOLYMER BOREALIS TECHNOLOGY OY (FI) 2010-11-04 US disclosed
EP-2220133-A1 POLYPROPYLENE COPOLYMER Borealis Technology OY (FI) 2010-08-25 EP disclosed
EP-2215131-A1 POLYETHYLENE COPOLYMER Borealis Technology OY (FI) 2010-08-11 EP disclosed
EP-1952970-B1 Use of polypropyplene having long chain branching to broaden the processing window in the injection strech blow molding BOREALIS TECH OY (FI) 2010-04-28 EP disclosed
US-20100063212-A1 USE OF POLYPROPYLENE HAVING CHAIN BRANCHING TO BROADEN THE PROCESSING WINDOW IN THE INJECTION STRETCH BLOW MOLDING BOREALIS TECHNOLOGY OY (FI) 2010-03-11 US disclosed
EP-1391482-B1 Polypropylene composition BOREALIS TECH OY (FI) 2009-05-20 EP disclosed
WO-2009059781-A1 POLYETHYLENE COPOLYMER BOREALIS TECHNOLOGY OY (FI) 2009-05-14 WO disclosed
EP-1294782-B1 USE OF MODIFIED OLEFIN POLYMERS FOR PRODUCING POLYOLEFIN PRODUCTS WITH IMPROVED TOUGHNESS, STRENGTH AND HEAT RESISTANCE BOREALIS POLYOLEFINE GMBH (AT) 2007-01-10 EP disclosed
WO-2006079449-A1 MULTILAYER STRUCTURES BOREALIS TECHNOLOGY OY (FI) 2006-08-03 WO disclosed
EP-1683631-A1 Multilayer structures Borealis Technology OY (FI) 2006-07-26 EP disclosed
US-6797778-B2 Use of modified olefin polymers for producing polyolefin products with improved toughness, strength and heat resistance BOREALIS GMBH (AU) 2004-09-28 US disclosed
EP-1391482-A1 Polypropylene composition Borealis GmbH (AT) 2004-02-25 EP disclosed
US-20030176590-A1 Use of modified olefin polymers for producing polyolefin products with improved toughness, strength and heat resistance BOREALIS GMBH (AT) 2003-09-18 US disclosed
EP-1294782-A1 USE OF MODIFIED OLEFIN POLYMERS FOR PRODUCING POLYOLEFIN PRODUCTS WITH IMPROVED TOUGHNESS, STRENGTH AND HEAT RESISTANCE Borealis GmbH (AT) 2003-03-26 EP disclosed
EP-1211284-A1 Semi-finished products or moulded materials of improved toughness made from propylene polymers Borealis GmbH (AT) 2002-06-05 EP disclosed
EP-1167404-A1 Polyolefin products with improved toughness, strength and heat resistance Borealis GmbH (AT) 2002-01-02 EP disclosed
WO-2001098385-A1 USE OF MODIFIED OLEFIN POLYMERS FOR PRODUCING POLYOLEFIN PRODUCTS WITH IMPROVED TOUGHNESS, STRENGTH AND HEAT RESISTANCE BOREALIS GMBH (AT) 2001-12-27 WO disclosed