Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9750091 | 0.76 | ALDH1A1 (0.50) | MAPTHPGDALDH1A1RAB9ANPC1 | |
| SCHEMBL9369 | 0.75 | ALDH1A1 (0.58) | MAPTHPGDALDH1A1MAPK1TDP1 | |
| SCHEMBL4897408 | 0.73 | ALDH1A1 (0.52) | MAPTHPGDALDH1A1RAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL18641492 | 0.73 | TSHR (0.55) | MAPTHPGDALDH1A1MAPK1TDP1 | |
| SCHEMBL1932038 | 0.71 | TLR9 (0.71) | MAPTALDH1A1RAB9ANPC1HSD17B3 | |
| SCHEMBL10082293 | 0.71 | TLR9 (0.71) | MAPTALDH1A1RAB9ANPC1HSD17B3 | |
| SCHEMBL9839598 | 0.70 | ALDH1A1 (0.42) | MAPTHPGDALDH1A1RAB9ANPC1 | |
| SCHEMBL1507037 | 0.69 | ALDH1A1 (0.50) | MAPTHPGDALDH1A1MAPK1TDP1 | |
| SCHEMBL9750077 | 0.69 | MAPT (0.53) | MAPTALDH1A1RAB9ANPC1KDM4E | |
| SCHEMBL75061 | 0.69 | APP (0.62) | MAPTALDH1A1RAB9ANPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644330-A4 | QUATERNARY NITROGEN HETEROCYCLIC COMPOUNDS FOR DETECTING AQUEOUS MONOSACCHARIDES IN PHYSIOLOGICAL FLUIDS | UNIV MARYLAND BIOTECH INST (US) | 2009-06-03 | — | — | EP | disclosed |
| EP-1644330-A2 | QUATERNARY NITROGEN HETEROCYCLIC COMPOUNDS FOR DETECTING AQUEOUS MONOSACCHARIDES IN PHYSIOLOGICAL FLUIDS | UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE (US) | 2006-04-12 | — | — | EP | disclosed |
| WO-2005000109-A2 | QUATERNARY NITROGEN HETEROCYCLIC COMPOUNDS FOR DETECTING AQUEOUS MONOSACCHARIDES IN PHYSIOLOGICAL FLUIDS | UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE (US) | 2005-01-06 | — | — | WO | disclosed |