SCHEMBL4897408

SCHEMBL4897408

CN(C)c1ccc(C(=CCC=C(c2ccc(N(C)C)cc2)c2ccc(N(C)C)cc2)c2ccc(N(C)C)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.52
HPGD P15428 3/20 0.52
MAPT P10636 2/20 0.52
TSHR P16473 4/20 0.50
ALOX15 P16050 3/20 0.50
MAPK1 P28482 3/20 0.50
CYP3A4 P08684 2/20 0.50
HSD17B10 Q99714 2/20 0.50
HBB P68871 1/20 0.50
RAB9A P51151 3/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
NPC1 O15118 2/20 0.45
TDP1 Q9NUW8 1/20 0.44
BCL2L1 Q07817 1/20 0.44
GFER P55789 1/20 0.42
PTGS1 P23219 1/20 0.42
PTGS2 P35354 1/20 0.42
APP P05067 1/20 0.42
HDAC1 Q13547 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14099863 0.92 RAB9A (0.58) ALDH1A1HPGDMAPTMAPK1RAB9A
SCHEMBL9750091 0.87 ALDH1A1 (0.50) ALDH1A1HPGDMAPTTSHRMAPK1
SCHEMBL9839509 0.84 ALDH1A1 (0.47) ALDH1A1HPGDMAPTTSHRMAPK1
Dibenzoylmethane SCHEMBL9838231 0.82 RAB9A (0.56) ALDH1A1HPGDMAPTALOX15MAPK1
SCHEMBL6937372 0.81 ALDH1A1 (0.56) ALDH1A1HPGDMAPTTSHRALOX15
SCHEMBL9815915 0.81 ALDH1A1 (0.56) ALDH1A1HPGDMAPTTSHRALOX15
Malonic Acid Diethyl Ester SCHEMBL9840328 0.80 ALDH1A1 (0.48) ALDH1A1HPGDMAPTTSHRMAPK1
SCHEMBL9840309 0.79 ALDH1A1 (0.45) ALDH1A1HPGDMAPTTSHRMAPK1
Benzenesulfonamide SCHEMBL9749590 0.79 CA2 (0.50) ALDH1A1HPGDRAB9AMEN1KMT2A
SCHEMBL672957 0.79 ALOX15 (0.44) ALDH1A1HPGDMAPTTSHRALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080194403-A1 Laser Recording Thermally Sensitive Recording Medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2008-08-14 US disclosed
EP-1707399-B1 LASER RECORDING TYPE HEAT-SENSITIVE RECORDING MEDIUM JUJO PAPER CO LTD (JP) 2007-11-28 EP disclosed
US-20070099798-A1 Laser recording thermally sensitive recording medium NAGAI TOMOAKI 2007-05-03 US disclosed
EP-1398169-B1 LASER RECORDING TYPE HEAT SENSITIVE RECORDING ELEMENT JUJO PAPER CO LTD (JP) 2006-11-15 EP disclosed
EP-1707399-A1 LASER RECORDING TYPE HEAT-SENSITIVE RECORDING MEDIUM Nippon Paper Industries Co., Ltd. (JP) 2006-10-04 EP disclosed
US-20040171485-A1 Laser recording type heat sensitive recording element NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2004-09-02 US disclosed
EP-0993965-B1 Thermally sensitive recording medium JUJO PAPER CO LTD (JP) 2004-03-31 EP disclosed
EP-1398169-A1 LASER RECORDING TYPE HEAT SENSITIVE RECORDING ELEMENT Nippon Paper Industries Co., Ltd. (JP) 2004-03-17 EP disclosed
US-6440897-B1 BIS-BENZOXAZINONE COMPOUND AS AN ULTRAVIOLET RAY ABSORBING AGENT NIPPON PAPER INDUSTRIES CO LTD (JP) 2002-08-27 US disclosed
EP-0993965-A2 Thermally sensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2000-04-19 EP disclosed