Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PD | P11413 | 1/20 | 0.57 |
| ▸ | CASP7 | P55210 | 1/20 | 0.57 |
| ▸ | CASP6 | P55212 | 1/20 | 0.57 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30934865 | 0.86 | G6PD (0.59) | G6PDCASP7CASP6HMGB1MMP2 | |
| SCHEMBL4444648 | 0.86 | G6PD (0.59) | G6PDCASP7CASP6HMGB1MMP2 | |
| SCHEMBL808482 | 0.84 | G6PD (0.57) | G6PDCASP7CASP6HMGB1MMP2 | |
| SCHEMBL30762619 | 0.84 | G6PD (0.57) | G6PDCASP7CASP6HMGB1MMP2 | |
| SCHEMBL5965437 | 0.84 | G6PD (0.57) | G6PDCASP7CASP6HMGB1MMP2 | |
| SCHEMBL5545298 | 0.84 | PARP1 (0.46) | G6PDCASP7CASP6ALDH1A1LMNA | |
| SCHEMBL27965749 | 0.82 | G6PD (0.55) | G6PDCASP7CASP6HMGB1MMP2 | |
| SCHEMBL27902532 | 0.82 | G6PD (0.55) | G6PDCASP7CASP6HMGB1MMP2 | |
| SCHEMBL6241910 | 0.82 | ABCB11 (0.62) | G6PDCASP7CASP6HMGB1MMP2 | |
| SCHEMBL11701728 | 0.82 | G6PD (0.55) | G6PDCASP7CASP6HMGB1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020109524-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-06-04 | — | — | WO | disclosed |
| US-7550510-B2 | Solid phase synthesis of arylretinamides | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2009-06-23 | — | — | US | disclosed |
| US-20040102650-A1 | Solid phase synthesis of arylretinamides | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-05-27 | — | — | US | disclosed |
| US-6696606-B2 | REACTING HEXACHLOROACETONE WITH TRIPHENYLPHOSPHINE; CHLORINATION OF RETINOIC ACID; THEN AROMATIC AMINE; ANTICANCER AGENTS | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION | 2004-02-24 | — | — | US | disclosed |
| US-20030105164-A1 | Solid phase synthesis of arylretinamides | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2003-06-05 | — | — | US | disclosed |
| WO-2003003987-A2 | SOLID PHASE SYNTHESIS OF ARYLRETINAMIDES | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2003-01-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040102650-A1 | Solid phase synthesis of arylretinamides | RARA, LRAT, NR2E3 | G6PD 2705/4885CASP7 70/4885CASP6 90/4885 |
| US-20030105164-A1 | Solid phase synthesis of arylretinamides | RARA, LRAT, NR2E3 | G6PD 2705/4885CASP7 70/4885CASP6 90/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.