SCHEMBL384453

SCHEMBL384453

C/C(C(=O)[O-])=C(\C)C(=O)[O-].c1ccc([Sn+2]c2ccccc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.38
CA4 P22748 1/20 0.38
CES2 O00748 3/20 0.37
CES1 P23141 3/20 0.37
SMN1; SMN2 Q16637 2/20 0.36
GAA P10253 2/20 0.36
NAPRT Q6XQN6 2/20 0.35
HSD17B10 Q99714 1/20 0.35
MAPT P10636 3/20 0.34
ALDH1A1 P00352 3/20 0.33
TSHR P16473 2/20 0.33
CYP3A4 P08684 1/20 0.33
ALOX5 P09917 1/20 0.33
AKR1C3 P42330 1/20 0.33
CA12 O43570 1/20 0.33
CA9 Q16790 1/20 0.33
GLA P06280 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
KMT2A Q03164 1/20 0.33
ALPL P05186 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL384455 1.00 CA2 (0.38) CA2CA4CES2CES1SMN1; SMN2
Acetic Acid SCHEMBL1140944 0.89 CA2 (0.42) CA2CA4CES2CES1SMN1; SMN2
Propionic Acid SCHEMBL29201796 0.78 CES2 (0.47) CA2CA4CES2CES1SMN1; SMN2
SCHEMBL14914905 0.78 TDP1 (0.38) CA2CA4CES2CES1SMN1; SMN2
Fumaric Acid SCHEMBL383745 0.76 CA2 (0.39) CA2CA4CES2CES1SMN1; SMN2
Succinic Acid SCHEMBL11314403 0.76 HDAC3 (0.48) CA2CA4CES2CES1SMN1; SMN2
Fumaric Acid SCHEMBL383748 0.76 CA2 (0.39) CA2CA4CES2CES1SMN1; SMN2
SCHEMBL384291 0.74 CES2 (0.43) CES2CES1SMN1; SMN2ALDH1A1TSHR
Adipic Acid SCHEMBL674486 0.72 HDAC1 (0.55) CA2CA4CES2CES1SMN1; SMN2
SCHEMBL383456 0.72 CES1 (0.52) CES2CES1GAAALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3851489-A1 MODIFIED MULTI-COMPONENT COPOLYMER, RUBBER COMPOSITION, RESIN COMPOSITION, TIRE AND RESIN PRODUCT BRIDGESTONE CORPORATION (JP) 2021-07-21 EP disclosed
EP-2098541-B1 METHOD FOR PRODUCING MODIFIED CONJUGATED DIENE POLYMER, MODIFIED CONJUGATED DIENE POLYMER, AND RUBBER COMPOSITION JSR CORP (JP) 2013-06-05 EP disclosed
US-8101671-B2 Polyolefin resin foam and the process for producing the same JSR CORPORATION (JP) 2012-01-24 US disclosed
US-20100317794-A1 METHOD FOR PRODUCING MODIFIED CONJUGATED DIENE POLYMER, MODIFIED CONJUGATED DIENE POLYMER, AND RUBBER COMPOSITION JSR CORPORATION (JP) 2010-12-16 US disclosed
EP-2098541-A1 METHOD FOR PRODUCING MODIFIED CONJUGATED DIENE POLYMER, MODIFIED CONJUGATED DIENE POLYMER, AND RUBBER COMPOSITION JSR Corporation (JP) 2009-09-09 EP disclosed
US-20090209670-A1 POLYOLEFIN RESIN FOAM AND THE PROCESS FOR PRODUCING THE SAME JSR CORPORATION (JP) 2009-08-20 US disclosed
EP-2000500-A1 POLYOLEFIN RESIN FOAM AND PROCESS FOR PRODUCTION THEREOF JSR Corporation (JP) 2008-12-10 EP disclosed
US-7294680-B2 Method of producing conjugated diene polymers with narrow molecular weight distribution and polymer produced JSR CORPORATION (JP) 2007-11-13 US disclosed
US-20060287433-A1 Thermoplastic elastomer composition and molding thereof JSR CORPORATION (JP) 2006-12-21 US disclosed
EP-1683832-A1 THERMOPLASTIC ELASTOMER COMPOSITION AND MOLDING THEREOF JSR Corporation (JP) 2006-07-26 EP disclosed
EP-1026181-B1 Method of producing conjugated diene polymer JSR CORP (JP) 2004-11-24 EP disclosed
US-20040147694-A1 Method of producing conjugated diene polymers with narrow molecular weight distribution and polymer produced JSR CORPORATION 2004-07-29 US disclosed
EP-0957115-B1 Method for producing conjugated diene polymers JSR CORP (JP) 2003-12-03 EP disclosed
EP-0863165-B1 Method of producing conjugated diene polymers JSR CORP (JP) 2003-06-04 EP disclosed
US-6391990-B1 Method of producing conjugated diene polymer JSR CORPORATION (JP) 2002-05-21 US disclosed
US-6255416-B1 POLYMERIZING CONJUGATED DIENE COMPOUND WITH CATALYST CONSISTING ESSENTIALLY OF COMPOUND CONTAINING RARE EARTH ELEMENT, ALUMOXANE, ORGANOALUMINUM COMPOUND, REACTION PRODUCT OF METAL HALIDE AND LEWIS BASE JSR CORPORATION (JP) 2001-07-03 US disclosed
EP-1026181-A1 Method of producing conjugated diene polymer JSR Corporation (JP) 2000-08-09 EP disclosed
EP-0957115-A1 Method for producing conjugated diene polymers JSR Corporation (JP) 1999-11-17 EP disclosed
EP-0863165-A1 Method of producing conjugated diene polymers JSR Corporation (JP) 1998-09-09 EP disclosed