Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 4/20 | 0.41 |
| ▸ | CES1 | P23141 | 4/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL384453 | 0.89 | CA2 (0.38) | CA2CA4CES2CES1SMN1; SMN2 | |
| SCHEMBL384455 | 0.89 | CA2 (0.38) | CA2CA4CES2CES1SMN1; SMN2 | |
| Propionic Acid SCHEMBL29201796 | 0.84 | CES2 (0.47) | CA2CA4CES2CES1SMN1; SMN2 | |
| SCHEMBL14914905 | 0.83 | TDP1 (0.38) | CA2CA4CES2CES1SMN1; SMN2 | |
| Fumaric Acid SCHEMBL383748 | 0.81 | CA2 (0.39) | CA2CA4CES2CES1CA1 | |
| Fumaric Acid SCHEMBL383745 | 0.81 | CA2 (0.39) | CA2CA4CES2CES1CA1 | |
| Succinic Acid SCHEMBL11314403 | 0.81 | HDAC3 (0.48) | CA2CA4CES2CES1SMN1; SMN2 | |
| Adipic Acid SCHEMBL674486 | 0.78 | HDAC1 (0.55) | CA2CA4CES2CES1CA1 | |
| Acetic Acid SCHEMBL106040 | 0.77 | CA2 (0.44) | CA2CA4CES2CES1CA1 | |
| (R)-3-Hydroxybutanoate SCHEMBL9198216 | 0.76 | CA2 (0.38) | CA2CES2CES1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4015592-B1 | CURABLE CONDENSATION COMPOUNDS ON THE BASIS OF ALKOXY-FUNCTIONAL POLYSILOXANES | EVONIK OPERATIONS GMBH (DE) | 2026-03-18 | — | — | EP | claimed |
| US-12460081-B2 | Curable condensation compounds based on alkoxy-functional polysiloxanes | EVONIK OPERATIONS GMBH (DE) | 2025-11-04 | — | — | US | claimed |
| US-12125606-B2 | Method and compositions to achieve long-term stable electrical conductivity in silicone material with carbon black as conductive fillers | Elkem Silicones USA Corp. (US) | 2024-10-22 | — | — | US | claimed |
| CN-115916903-B | Method and composition for achieving long-term stable conductivity of silicone materials using carbon black as conductive filler | 埃肯有机硅美国公司 | 2024-09-27 | — | — | CN | claimed |
| CN-118620307-A | Anti-aging flame-retardant master batch for PE artificial grass filaments and preparation method thereof | 巨奇塑胶江苏有限公司 | 2024-09-10 | — | — | CN | claimed |
| CN-117417723-A | Light and moisture dual-cured anisotropic conductive adhesive and curing method thereof | 深圳先进电子材料国际创新研究院 | 2024-01-19 | — | — | CN | claimed |
| EP-4186954-A1 | CURABLE CONDENSATION COMPOUNDS BASED ON ALKOXY-FUNCTIONAL POLYSILOXANES | Evonik Operations GmbH (DE) | 2023-05-31 | — | — | EP | claimed |
| CN-116162247-A | Curable condensation compounds based on alkoxy-functional polysiloxanes | 赢创运营有限公司 | 2023-05-26 | — | — | CN | claimed |
| US-20230159756-A1 | Curable condensation compounds based on alkoxy-functional polysiloxanes | EVONIK OPERATIONS GMBH (DE) | 2023-05-25 | — | — | US | claimed |
| EP-4161996-A1 | METHOD AND COMPOSITIONS TO ACHIEVE LONG-TERM STABLE ELECTRICAL CONDUCTIVITY IN SILICONE MATERIAL WITH CARBON BLACK AS CONDUCTIVE FILLERS | Elkem Silicones USA Corp. (US) | 2023-04-12 | — | — | EP | claimed |
| CN-115916903-A | Method and composition for achieving long-term stable conductivity of organosilicon materials using carbon black as conductive filler | 埃肯有机硅美国公司 | 2023-04-04 | — | — | CN | claimed |
| EP-4015592-A2 | CURABLE CONDENSATION COMPOUNDS ON THE BASIS OF ALKOXY-FUNCTIONAL POLYSILOXANES | Evonik Operations GmbH (DE) | 2022-06-22 | — | — | EP | claimed |
| EP-4011992-A1 | CURABLE CONDENSATION COMPOUNDS ON THE BASIS OF ALKOXY-FUNCTIONAL POLYSILOXANES | Evonik Operations GmbH (DE) | 2022-06-15 | — | — | EP | claimed |
| CN-114621445-A | Curable condensation compounds based on alkoxy-functional polysiloxanes | 赢创运营有限公司 | 2022-06-14 | — | — | CN | claimed |
| US-20220177652-A1 | Curable condensation compounds based on alkoxy-functional polysiloxanes | EVONIK OPERATIONS GMBH (DE) | 2022-06-09 | — | — | US | claimed |
| EP-3269775-B1 | PRIMER FOR AN ADHESIVE | STRONGBOND B V (NL) | 2020-12-02 | — | — | EP | claimed |
| EP-0802236-B1 | CURABLE POLYMETHYLSILSESQUIOXANE COMPOSITION | DOW CORNING ASIA LTD (JP) | 2002-04-10 | — | — | EP | claimed |
| US-12637598-B2 | Heat-crosslinkable adhesive composition forming a heat-stable adhesive seal | BOSTIK SA (FR) | 2026-05-26 | — | — | US | disclosed |
| US-4036810-A | METAL SALT OF A CARBOXYLIC ACID OR AN A-OLEFIN-MALEIC ANHYDRIDE COPOLYMER | HOOKER CHEMICALS & PLASTICS CORPORATION (US) | 1977-07-19 | — | — | US | disclosed |
| US-3933740-A | Halogen containing polymeric resins having improved heat and light stability | HOOKER CHEMICALS & PLASTICS CORPORATION (US) | 1976-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12637598-B2 | Heat-crosslinkable adhesive composition forming a heat-stable adhesive seal | HSPA1A, HSPB1, HSPA1B | CA2 4605/4885CA4 4299/4885CES2 1729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.