Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA known ✓ | P35790 | 10/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1063959 | 0.98 | ALDH1A1 (0.46) | CHKAALDH1A1TSHRALOX15HSD17B10 | |
| Hydrochloric Acid SCHEMBL29199774 | 0.95 | ALDH1A1 (0.43) | CHKAALDH1A1TSHRALOX15HSD17B10 | |
| SCHEMBL161677 | 0.90 | ALDH1A1 (0.39) | CHKAALDH1A1TSHRALOX15HSD17B10 | |
| SCHEMBL4531332 | 0.90 | ALDH1A1 (0.39) | CHKAALDH1A1TSHRALOX15HSD17B10 | |
| SCHEMBL1185630 | 0.88 | CHKA (0.41) | CHKAALDH1A1TSHRALOX15HSD17B10 | |
| SCHEMBL1185633 | 0.86 | CHKA (0.36) | CHKAALDH1A1TSHRALOX15HSD17B10 | |
| SCHEMBL7995708 | 0.86 | CHKA (0.36) | CHKAALDH1A1TSHRALOX15HSD17B10 | |
| Acetonitrile SCHEMBL28221268 | 0.86 | CHKA (0.36) | CHKAALDH1A1TSHRALOX15HSD17B10 | |
| SCHEMBL3630115 | 0.86 | CHKA (0.36) | CHKAALDH1A1TSHRALOX15HSD17B10 | |
| Trifluoromethanesulfonic Acid SCHEMBL4459808 | 0.79 | NSD2 (0.37) | ALDH1A1TSHRALOX15HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117945893-A | Method for separating succinic acid and adipic acid mixture | 开滦（集团）有限责任公司 | 2024-04-30 | — | — | CN | claimed |
| WO-2023069278-A1 | CHEMICAL REAGENTS FOR THE ACTIVATION OF POLYSACCHARIDES IN THE PREPARATION OF CONJUGATE VACCINES | FINA BIOSOLUTIONS, LLC (US) | 2023-04-27 | — | — | WO | claimed |
| US-20230122876-A1 | Chemical Reagents for the Activation of Polysaccharides in the Preparation of Conjugate Vaccines | FINA BIOSOLUTIONS, LLC (US) | 2023-04-20 | — | — | US | claimed |
| CN-117945893-A | Method for separating succinic acid and adipic acid mixture | 开滦（集团）有限责任公司 | 2024-04-30 | — | — | CN | disclosed |
| WO-2023069278-A1 | CHEMICAL REAGENTS FOR THE ACTIVATION OF POLYSACCHARIDES IN THE PREPARATION OF CONJUGATE VACCINES | FINA BIOSOLUTIONS, LLC (US) | 2023-04-27 | — | — | WO | disclosed |
| WO-2023069278-A1 | CHEMICAL REAGENTS FOR THE ACTIVATION OF POLYSACCHARIDES IN THE PREPARATION OF CONJUGATE VACCINES | FINA BIOSOLUTIONS, LLC (US) | 2023-04-27 | — | — | WO | disclosed |
| US-20230122876-A1 | Chemical Reagents for the Activation of Polysaccharides in the Preparation of Conjugate Vaccines | FINA BIOSOLUTIONS, LLC (US) | 2023-04-20 | — | — | US | disclosed |
| US-20230122876-A1 | Chemical Reagents for the Activation of Polysaccharides in the Preparation of Conjugate Vaccines | FINA BIOSOLUTIONS, LLC (US) | 2023-04-20 | — | — | US | disclosed |
| US-10444220-B2 | Controlled tunnel gap device for sequencing polymers | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2019-10-15 | — | — | US | disclosed |
| US-20180224422-A1 | CONTROLLED TUNNEL GAP DEVICE FOR SEQUENCING POLYMERS | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY | 2018-08-09 | — | — | US | disclosed |
| US-9810681-B2 | Controlled tunnel gap device for sequencing polymers | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2017-11-07 | — | — | US | disclosed |
| EP-1044372-B1 | Method for determining an analyte in a sample using a flow matrix which comprises addition of reagents at two or more positions of the matrix | PHARMACIA DIAGNOSTICS AB (SE) | 2003-09-03 | — | — | EP | disclosed |
| EP-1305327-A2 | TRIPHOSPHATE OLIGONUCLEOTIDE MODIFICATION REAGENTS AND USES THEREOF | Schwartz, David A. (US) | 2003-05-02 | — | — | EP | disclosed |
| WO-2002010432-A2 | TRIPHOSPHATE OLIGONUCLEOTIDE MODIFICATION REAGENTS AND USES THEREOF | SCHWARTZ DAVID A (US) | 2002-02-07 | — | — | WO | disclosed |
| WO-2002010431-A2 | FUNCTIONAL BIOPOLYMER MODIFICATION REAGENTS AND USES THEREOF | SCHWARTZ DAVID A (US) | 2002-02-07 | — | — | WO | disclosed |
| EP-1044372-A1 | ANALYTICAL METHOD COMPRISING ADDITION IN TWO OR MORE POSITIONS AND A DEVICE AND TEST KIT THEREFOR | Pharmacia & Upjohn Diagnostics AB (SE) | 2000-10-18 | — | — | EP | disclosed |
| EP-1044376-A1 | ANALYTICAL METHOD USING PARTICLES AND TEST KIT FOR PERFORMING THE METHOD | Pharmacia & Upjohn Diagnostics AB (SE) | 2000-10-18 | — | — | EP | disclosed |
| WO-1999036780-A1 | ANALYTICAL METHOD USING PARTICLES AND TEST KIT FOR PERFORMING THE METHOD | PHARMACIA & UPJOHN DIAGNOSTICS AB (SE) | 1999-07-22 | — | — | WO | disclosed |
| WO-1999036776-A1 | ANALYTICAL METHOD COMPRISING ADDITION IN TWO OR MORE POSITIONS AND A DEVICE AND TEST KIT THEREFOR | PHARMACIA & UPJOHN DIAGNOSTICS AB (SE) | 1999-07-22 | — | — | WO | disclosed |
| WO-1998001545-A1 | MODIFIED LACTATE DEHYDROGENASE, PROCESS FOR ITS PREPARATION AND ITS USE | BOEHRINGER MANNHEIM GMBH (DE) | 1998-01-15 | — | — | WO | disclosed |