Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CHKA | P35790 | 7/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1063959 | 0.98 | ALDH1A1 (0.46) | ALDH1A1TSHRALOX15HSD17B10CHKA | |
| Bromide SCHEMBL384556 | 0.95 | CHKA (0.47) | ALDH1A1TSHRALOX15HSD17B10CHKA | |
| SCHEMBL161677 | 0.90 | ALDH1A1 (0.39) | ALDH1A1TSHRALOX15HSD17B10CHKA | |
| SCHEMBL4531332 | 0.90 | ALDH1A1 (0.39) | ALDH1A1TSHRALOX15HSD17B10CHKA | |
| SCHEMBL1185630 | 0.88 | CHKA (0.41) | ALDH1A1TSHRALOX15HSD17B10CHKA | |
| Acetonitrile SCHEMBL28221268 | 0.86 | CHKA (0.36) | ALDH1A1TSHRALOX15HSD17B10CHKA | |
| SCHEMBL3630115 | 0.86 | CHKA (0.36) | ALDH1A1TSHRALOX15HSD17B10CHKA | |
| SCHEMBL7995708 | 0.86 | CHKA (0.36) | ALDH1A1TSHRALOX15HSD17B10CHKA | |
| SCHEMBL1185633 | 0.86 | CHKA (0.36) | ALDH1A1TSHRALOX15HSD17B10CHKA | |
| SCHEMBL1193751 | 0.79 | CHKA (0.32) | ALDH1A1TSHRALOX15HSD17B10CHKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117945893-A | Method for separating succinic acid and adipic acid mixture | 开滦（集团）有限责任公司 | 2024-04-30 | — | — | CN | disclosed |