Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HBB | P68871 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.31 |
| ▸ | FNTB | P49356 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3630115 | 1.00 | CHKA (0.36) | CHKAALDH1A1MAPTTSHRALOX15 | |
| SCHEMBL1185633 | 0.89 | CHKA (0.36) | CHKAALDH1A1MAPTTSHRALOX15 | |
| SCHEMBL1063959 | 0.88 | ALDH1A1 (0.46) | CHKAALDH1A1MAPTTSHRALOX15 | |
| Bromide SCHEMBL384556 | 0.86 | CHKA (0.47) | CHKAALDH1A1MAPTTSHRALOX15 | |
| Hydrochloric Acid SCHEMBL29199774 | 0.86 | ALDH1A1 (0.43) | CHKAALDH1A1MAPTTSHRALOX15 | |
| SCHEMBL161677 | 0.85 | ALDH1A1 (0.39) | CHKAALDH1A1MAPTTSHRALOX15 | |
| SCHEMBL4531332 | 0.85 | ALDH1A1 (0.39) | CHKAALDH1A1MAPTTSHRALOX15 | |
| Acetonitrile SCHEMBL28221268 | 0.81 | CHKA (0.36) | CHKAALDH1A1MAPTTSHRALOX15 | |
| SCHEMBL1185630 | 0.79 | CHKA (0.41) | CHKAALDH1A1MAPTTSHRALOX15 | |
| Trifluoromethanesulfonic Acid SCHEMBL4459808 | 0.78 | NSD2 (0.37) | ALDH1A1TSHRALOX15HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6287806-B1 | CULTURING TRANSFORMANT WHICH EXPRESSES A FUSION PROTEIN HAVING CYSTEINE AT N-TERMINAL AND CYSTEINE-FREE PEPTIDE LIGATED TO N-TERMINAL, CLEAVING PEPTIDE AT AMINO GROUP SIDE OF CYSTEINE BY CYANYLATION AND THEN HYDROLYSIS OR AMINOLYSIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-09-11 | — | — | US | disclosed |
| US-5861284-A | CULTIVATING A TRANSFORMANT HAVING A VECTOR CARRYING A GENE CODING HUMAN PARATHYROID HORMONE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-01-19 | — | — | US | disclosed |
| US-5856138-A | DERIVATIVES USEFUL AS HORMONE REMEDIES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-01-05 | — | — | US | disclosed |
| EP-0528271-B1 | Human parathyroid hormone muteins and production thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-04-23 | — | — | EP | disclosed |
| EP-0499990-B1 | Method for producing cysteine-free peptides | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1996-05-15 | — | — | EP | disclosed |
| EP-0528271-A1 | Human parathyroid hormone muteins and production thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-02-24 | — | — | EP | disclosed |
| EP-0499990-A2 | Method for producing cysteine-free peptides | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-08-26 | — | — | EP | disclosed |