SCHEMBL3845719

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3846460	0.90	ADRA1B (0.50)	DRD2DRD3HTR1AADRA1AADRA1B
	SCHEMBL3844984	0.89	ALDH1A1 (0.56)	FFAR4DRD2DRD3HTR1AADRA1A
	SCHEMBL3844154	0.87	FFAR4 (0.48)	FFAR4DRD2DRD3HTR1AADRA1B
	SCHEMBL3845174	0.86	DRD2 (0.59)	DRD2DRD3HTR1AADRA1AADRA1B
	SCHEMBL3853707	0.86	DRD2 (0.48)	DRD2DRD3HTR1AADRA1AADRA1B
	SCHEMBL3843688	0.86	ADRA1B (0.49)	DRD2DRD3ADRA1BUSP2CHRM2
	SCHEMBL13630498	0.86	USP2 (0.52)	FFAR4DRD2DRD3HTR1AHTT
	SCHEMBL3843651	0.85	DRD4 (0.47)	DRD2DRD3HTR1AADRA1AADRA1B
	SCHEMBL3845788	0.85	MAPT (0.45)	DRD2DRD3HTTLMNAMAPT
	SCHEMBL3854012	0.84	DRD2 (0.57)	DRD2DRD3HTR1AADRA1AADRA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.