SCHEMBL383535

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6551809	0.88	AKR1C3 (0.72)	GRIK1GRIK2AKR1C3AKR1C2MPO
	SCHEMBL31060427	0.88	AKR1C3 (0.72)	GRIK1GRIK2AKR1C3AKR1C2MPO
	SCHEMBL6431740	0.85	GRIK1 (1.00)	GRIK1GRIK2MEN1KMT2A
	SCHEMBL9515604	0.85	GRIK1 (0.69)	GRIK1GRIK2AKR1C3AKR1C2MEN1
	SCHEMBL15397409	0.83	AKR1C3 (0.60)	GRIK1GRIK2AKR1C3AKR1C2MPO
	SCHEMBL384593	0.82	FABP4 (0.65)	GRIK1GRIK2AKR1C3AKR1C2MPO
	SCHEMBL31500236	0.80	AKR1C3 (0.70)	GRIK1AKR1C3AKR1C2MEN1KMT2A
	SCHEMBL901641	0.80	AKR1C3 (0.80)	AKR1C3AKR1C2MEN1KMT2ALMNA
	SCHEMBL28404353	0.80	AKR1C3 (0.81)	GRIK1AKR1C3AKR1C2MEN1KMT2A
	SCHEMBL29835007	0.80	MPO (0.81)	GRIK1AKR1C3AKR1C2MPOMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.