SCHEMBL3846352

SCHEMBL3846352

C#Cc1cc[c]c(-c2ccccc2)c1-c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3841805 0.78 LMNA (0.31) LMNAMAPTHTT
SCHEMBL891578 0.72 LMNA (0.36) LMNAMAPTHTT
SCHEMBL3846385 0.71
SCHEMBL15757626 0.71 LMNA (0.34) LMNAMAPTHTT
SCHEMBL8112261 0.71 CYP2A6 (0.37) LMNAMAPTHTT
SCHEMBL7070227 0.71 BRD4 (0.36) LMNAMAPTHTT
SCHEMBL15757985 0.71 ALDH1A1 (0.37) LMNAMAPTHTT
SCHEMBL10416405 0.71 NRP1 (0.37) LMNAMAPT
SCHEMBL3848174 0.70 CYP19A1 (0.36)
SCHEMBL3840723 0.68 CYP19A1 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090318610-A1 ORGANIC INSULATING MATERIALS, VARNISHES FOR ORGANIC INSULATING FILM EMPLOYING THEM, ORGANIC INSULATING FILMS AND SEMICONDUCTOR DEVICES SUMITOMO BAKELITE CO., LTD (JP) 2009-12-24 US disclosed
EP-2117009-A1 ORGANIC INSULATING MATERIAL, VARNISH FOR ORGANIC INSULATING FILM USING THE SAME, ORGANIC INSULATING FILM AND SEMICONDUCTOR DEVICE Sumitomo Bakelite Co., Ltd. (JP) 2009-11-11 EP disclosed