SCHEMBL3846962

SCHEMBL3846962

CC(C)(C)c1ccc(O)c(C23CC4CC(CC(C4)C2)C3)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.47
KMT2A Q03164 4/20 0.47
GAA P10253 2/20 0.47
POLB P06746 1/20 0.47
GFER P55789 1/20 0.47
ALDH1A1 P00352 3/20 0.47
HPGD P15428 2/20 0.47
ALOX15 P16050 2/20 0.47
HSD17B10 Q99714 2/20 0.47
TDP1 Q9NUW8 1/20 0.47
RARB P10826 5/20 0.47
RARA P10276 5/20 0.47
RARG P13631 4/20 0.47
MAPT P10636 2/20 0.46
KDM4E B2RXH2 1/20 0.46
TP53 P04637 1/20 0.46
CYP3A4 P08684 1/20 0.46
ALOX12 P18054 1/20 0.46
MAPK1 P28482 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26632589 0.85 RARB (0.43) MEN1KMT2AGAAPOLBGFER
SCHEMBL27416250 0.84 CYP3A4 (0.44) MEN1KMT2AGAAPOLBGFER
SCHEMBL549625 0.81 MEN1 (0.40) MEN1KMT2AGAAPOLBGFER
SCHEMBL15771052 0.81 PTPN11 (0.46) MEN1KMT2AGAAPOLBGFER
SCHEMBL27199184 0.81 MEN1 (0.40) MEN1KMT2AGAAPOLBGFER
SCHEMBL22453051 0.81 MEN1 (0.33) MEN1KMT2AGAAPOLBGFER
SCHEMBL396121 0.78 MEN1 (0.51) MEN1KMT2AGAAPOLBGFER
SCHEMBL3755595 0.78 MEN1 (0.55) MEN1KMT2AGAAPOLBGFER
SCHEMBL549446 0.76 MEN1 (0.73) MEN1KMT2AGAAPOLBGFER
SCHEMBL3855891 0.76 HDAC11 (0.37) MEN1KMT2ATDP1RARBRARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250353942-A1 Modified Pyridine-2,6-Bis(Phenylenephenolate) Complexes with Enhanced Solubility that are Useful as Catalyst Components for Olefin Polymerization EXXONMOBIL CHEMICAL PATENTS INC (US) 2025-11-20 US disclosed
US-20250353867-A1 Substituted Pyridine-2,6-Bis(Phenylenephenolate) Complexes with Enhanced Solubility that are Useful as Catalyst Components for Olefin Polymerization EXXONMOBIL CHEMICAL PATENTS INC (US) 2025-11-20 US disclosed
US-20250277066-A1 Substituted Pyridine-2,6-Bis(Phenylenephenolate) Complexes with Enhanced Solubility that are Useful as Catalyst Components for Olefin Polymerization EXXONMOBIL CHEMICAL PATENTS INC (US) 2025-09-04 US disclosed
EP-4196507-B1 CYCLIC CONTAINING POLYMER COMPOSITIONS OBTAINED USING TRANSITION METAL BIS(PHENOLATE) CATALYST COMPLEXES AND PROCESS FOR PRODUCTION THEREOF EXXONMOBIL CHEMICAL PATENTS INC (US) 2025-05-21 EP disclosed
EP-4519332-A1 SUBSTITUTED PYRIDINE-2,6-BIS (PHENYLENEPHENOLATE) COMPLEXES WITH ENHANCED SOLUBILITY THAT ARE USEFUL AS CATALYST COMPONENTS FOR OLEFIN POLYMERIZATION ExxonMobil Chemical Patents Inc. (US) 2025-03-12 EP disclosed
EP-4519330-A1 MODIFIED PYRIDINE-2,6-BIS(PHENYLENEPHENOLATE) COMPLEXES WITH ENHANCED SOLUBILITY THAT ARE USEFUL AS CATALYST COMPONENTS FOR OLEFIN POLYMERIZATION ExxonMobil Chemical Patents Inc. (US) 2025-03-12 EP disclosed
CN-119487085-A Modified pyridine-2, 6-bis (phenylene phenoxide) complexes having enhanced solubility useful as olefin polymerization catalyst components 埃克森美孚化学专利公司 2025-02-18 CN disclosed
CN-118598909-B Preparation and application of OP bidentate fifth subgroup pentavalent metal complex 天津大学 2025-01-24 CN disclosed
CN-118598909-A Preparation and application of OP bidentate fifth subgroup pentavalent metal complex 天津大学 2024-09-06 CN disclosed
CN-115315453-B Propylene copolymers obtained using transition metal bis (phenoxide) catalyst complexes and homogeneous process for producing the same 埃克森美孚化学专利公司 2024-08-30 CN disclosed
US-20200384450-A1 CATALYSTS AND METHODS FOR EPOXIDE-BASED POLYMERIZATIONS CORNELL UNIVERSITY 2020-12-10 US disclosed
US-20200384450-A1 CATALYSTS AND METHODS FOR EPOXIDE-BASED POLYMERIZATIONS CORNELL UNIVERSITY 2020-12-10 US disclosed
WO-2020167799-A1 SUPPORTED TRANSITION METAL BIS (PHENOLATE) COMPLEXES AND THEIR USE AS CATALYSTS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2020-08-20 WO disclosed
WO-2020167821-A1 TRANSITION METAL BIS(PHENOLATE) COMPLEXES AND THEIR USE AS CATALYSTS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2020-08-20 WO disclosed
US-20200255553-A1 Transition Metal Bis(Phenolate) Complexes and Their Use as Catalysts for Olefin Polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2020-08-13 US disclosed
US-20200255561-A1 Supported Transition Metal Bis(Phenolate) Complexes and Their Use as Catalysts for Olefin Polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2020-08-13 US disclosed
CN-101547885-A Adamantane derivative, process for producing the same, and resin composition containing adamantane derivative IDEMITSU KOSAN CO (JP) 2009-09-30 CN disclosed
US-20090149555-A1 METHOD FOR PREPARING POLYHYDROXYALKANOATES, POLYMERS THUS OBTAINED, COMPOSITIONS COMPRISING THEM AND THEIR USES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2009-06-11 US disclosed
US-6326397-B1 OSTEOPOROSIS HOFFMAN-LA ROCHE INC. 2001-12-04 US disclosed
CN-1117966-A Biphenyl derivatives EISAI CO LTD (JP) 1996-03-06 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090149555-A1 METHOD FOR PREPARING POLYHYDROXYALKANOATES, POLYMERS THUS OBTAINED, COMPOSITIONS COMPRISING THEM AND THEIR USES HACL2, DECR1, MGLL MEN1 3930/4885KMT2A 3037/4885GAA 2503/4885
US-20250353867-A1 Substituted Pyridine-2,6-Bis(Phenylenephenolate) Complexes with Enhanced Solubility that are Useful as Catalyst Components for Olefin Polymerization HPD, YAP1, PAH MEN1 4834/4885KMT2A 2991/4885GAA 4567/4885
US-20200255561-A1 Supported Transition Metal Bis(Phenolate) Complexes and Their Use as Catalysts for Olefin Polymerization CCNA1, CCNE2, CCNT1 MEN1 2507/4885KMT2A 503/4885GAA 3392/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.