Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.58 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.58 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.58 |
| ▸ | FNTA | P49354 | 12/20 | 0.54 |
| ▸ | FNTB | P49356 | 12/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | KDM1A | O60341 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12442271 | 0.87 | FNTA (0.68) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL9105247 | 0.84 | ALDH1A1 (0.63) | ALDH1A1KDM4ERECQLLMNA | |
| SCHEMBL7278612 | 0.82 | HDAC3 (0.59) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL9394251 | 0.81 | HDAC3 (0.58) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL5717673 | 0.80 | GAA (0.56) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL30805762 | 0.79 | HDAC3 (0.64) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL29828250 | 0.79 | HDAC3 (0.64) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL27814502 | 0.79 | GABBR2 (0.69) | ALDH1A1KDM4ERECQLLMNA | |
| SCHEMBL12585094 | 0.77 | FNTA (0.85) | FNTAFNTBALDH1A1KDM4ERECQL | |
| SCHEMBL6102382 | 0.77 | ALPL (0.45) | FNTAFNTBALDH1A1KDM4ERECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099815-A2 | NOVEL AMIDES ACTING ON THE ADENOSINE RECEPTORS | Acure Pharma AB (SE) | 2009-09-16 | — | — | EP | disclosed |
| WO-2008058679-A2 | NOVEL AMIDES ACTING ON THE ADENOSINE RECEPTORS | ACURE PHARMA AB (SE) | 2008-05-22 | — | — | WO | disclosed |